Rôle du complexe NF45-NF90 dans la régulation post-transcriptionnelle du cycle cellulaire

S Nourreddine - 2021 - papyrus.bib.umontreal.ca
Le cycle cellulaire eucaryote se divise en une série de phases ordonnées qui ont pour
finalité la division cellulaire. Ce processus est primordial dans la prolifération des cellules …

Phosphorylation at serine 482 affects stability of NF90 and its functional role in mitosis

NL Smith, WK Miskimins - Cell proliferation, 2011 - Wiley Online Library
Objectives: NF90 is a multifunctional double‐strand RNA binding protein with documented
roles in transcription, mRNA stability, translation, RNA processing and transport, and mitosis …

[HTML][HTML] NF90 stabilizes cyclin E1 mRNA through phosphorylation of NF90-Ser382 by CDK2

D Ding, H Huang, Q Li, W Yu, C Wang, H Ma, J Wu… - Cell death …, 2020 - nature.com
Abstract Nuclear factor 90 (NF90), an RNA-binding protein, has been implicated in
regulating interleukin-2 (IL-2) and the immune response. It was recently reported that NF90 …

[HTML][HTML] NF45 and NF90 regulate mitotic gene expression by competing with Staufen-mediated mRNA decay

S Nourreddine, G Lavoie, J Paradis, KB El Kadhi… - Cell reports, 2020 - cell.com
In human cells, the expression of∼ 1,000 genes is modulated throughout the cell cycle.
Although some of these genes are controlled by specific transcriptional programs, very little …

Nuclear factor 45 (NF45) is a regulatory subunit of complexes with NF90/110 involved in mitotic control

D Guan, N Altan-Bonnet, AM Parrott… - … and cellular biology, 2008 - Am Soc Microbiol
Abstract Nuclear factor 90 (NF90) and its C-terminally extended isoform, NF110, have been
isolated as DNA-and RNA-binding proteins together with the less-studied protein NF45 …

Regulation of cell cycle of hepatocellular carcinoma by NF90 through modulation of cyclin E1 mRNA stability

W Jiang, H Huang, L Ding, P Zhu, H Saiyin, G Ji, J Zuo… - Oncogene, 2015 - nature.com
Activation of cyclin E1, a key regulator of the G1/S cell-cycle transition, has been implicated
in many cancers including hepatocellular carcinoma (HCC). Although much is known about …

The Two Faces of NF? B in Cell Survival Responses

B Graham, SB Gibson - Cell Cycle, 2005 - Taylor & Francis
Activation of NF? B is controlled by a diverse range of stimuli including growth factors, and
apoptotic inducers, but paradoxically these stimuli seem to activate the same NF? B …

[HTML][HTML] The atypical ubiquitin ligase RNF31 stabilizes estrogen receptor α and modulates estrogen-stimulated breast cancer cell proliferation

J Zhu, C Zhao, A Kharman-Biz, T Zhuang, P Jonsson… - Oncogene, 2014 - nature.com
Estrogen receptor α (ERα) is initially expressed in the majority of breast cancers and
promotes estrogen-dependent cancer progression by regulating the transcription of genes …

Reprogramming RelA

KJ Campbell, ND Perkins - Cell Cycle, 2004 - Taylor & Francis
The diversity of activators and targets of the NF-? B transcription factor family demandsthat
there be regulatory mechanisms in place to control the specificity with which genesunder …

Expression of NF45 correlates with malignant grade in gliomas and plays a pivotal role in tumor growth

Q Huang, X He, X Qiu, X Liu, G Sun, J Guo, Z Ding… - Tumor Biology, 2014 - Springer
Nuclear factor of activated T cells 45 kDa (NF45), is a transcription factor that interacts with
NF90 to regulate gene expression. It has been proved to be associated with tumor …