MYC is a proto-oncogene that encodes a powerful regulator of transcription and cellular
programs essential for normal development, as well as the growth and survival of various …

MYC regulates a complex biological program by transcriptionally activating and repressing
its numerous target genes. As such, MYC is a master regulator of many processes, including …

The transcription factor MYC plays a pivotal role in regulating various cellular processes and
has been implicated in tumorigenesis across multiple cancer types. MYC has emerged as a …

MYC is a transcription factor that controls the expression of a large fraction of cellular genes
linked to cell cycle progression, metabolism and differentiation. MYC deregulation in tumors …

The MYC transcription factor, encoded by the c‐MYC proto‐oncogene, is activated by
growth‐promoting signals, and is a key regulator of biosynthetic and metabolic pathways …

MYC is a multifunctional transcription factor that is deregulated in many human cancers.
MYC impacts a collaborative genetic program that orchestrates cell proliferation …

MYC is a target of the Wnt signalling pathway and governs numerous cellular and
developmental programmes hijacked in cancers. The amplification of MYC is a frequently …

Cancer cells must rewire cellular metabolism to satisfy the demands of unbridled growth and
proliferation. As such, most human cancers differ from normal counterpart tissues by a …

MAPK signaling pathways are constitutively active in colon cancer and also promote
acquired resistance to MEK1 inhibition. Here, we demonstrate that BRAFV600E-mutated …

MYB transcription factors are encoded by a large family of highly conserved genes from
plants to vertebrates. There are three members of the MYB gene family in human, namely …