Around a quarter of neurons in laminae I–II of the dorsal horn are inhibitory interneurons.
These play an important role in modulating somatosensory information, including that …

In order to understand how nociceptive information is processed in the spinal dorsal horn we
need to unravel the complex synaptic circuits involving interneurons, which constitute the …

Background Inhibitory interneurons in the superficial dorsal horn play important roles in
modulating sensory transmission, and these roles are thought to be performed by distinct …

Lamina II contains a large number of interneurons involved in modulation and transmission
of somatosensory (including nociceptive) information. However, its neuronal circuitry is …

Background: The opioid peptide dynorphin is expressed by certain neurons in the superficial
dorsal horn of the spinal cord, but little is known about the types of cell that contain …

If we are to stand any chance of understanding the circuitry of the superficial dorsal horn, it is
imperative that we can identify which classes of interneuron are excitatory and which are …

Background: Inhibitory interneurons constitute 30-40% of neurons in laminae I-III and have
an important antinociceptive role. However, because of the difficulty in classifying them we …

GABAergic interneurons represent∼ 15% to 20% of all cortical neurons, but their diversity
grants them unique roles in cortical circuits. In the barrel cortex, responses of excitatory …

Laminae I-III of the spinal dorsal horn contain many inhibitory interneurons that use GABA
and/or glycine as a neurotransmitter. Distinct neurochemical populations can be recognised …

Background Excitatory interneurons account for the majority of neurons in laminae I–III, but
their functions are poorly understood. Several neurochemical markers are largely restricted …