Carbohydrate polymer-based bioadhesive formulations and their potentials for the treatment of ocular diseases: a review

X Tang, J Liu, R Yan, Q Peng - International Journal of Biological …, 2023 - Elsevier
Eyes are directly exposed to the outer environment and susceptible to infections, leading to
various ocular disorders. Local medication is preferred to treat eye diseases due to its …

Mucoadhesive polymers for enhancing retention in ocular drug delivery: a critical review

A Khare, K Grover, P Pawar, I Singh - Reviews of Adhesion and …, 2014 - raajournal.com
Ocular drug delivery is a very challenging task faced by pharmaceutical scientists, inspire of
the fact that eye is the most sensitive and accessible organ for the delivery of drugs. A major …

[HTML][HTML] Polysaccharides in ocular drug delivery

N Dubashynskaya, D Poshina, S Raik, A Urtti… - Pharmaceutics, 2019 - mdpi.com
Polysaccharides, such as cellulose, hyaluronic acid, alginic acid, and chitosan, as well as
polysaccharide derivatives, have been successfully used to augment drug delivery in the …

[HTML][HTML] Strategies for improving ocular drug bioavailability and corneal wound healing with chitosan-based delivery systems

T Irimia, MV Ghica, L Popa, V Anuţa, AL Arsene… - Polymers, 2018 - mdpi.com
The main inconvenience of conventional eye drops is the rapid washout of the drugs due to
nasolacrimal drainage or ophthalmic barriers. The ocular drug bioavailability can be …

Insight on updates in polysaccharides for ocular drug delivery

NS Chandra, S Gorantla, S Priya, G Singhvi - Carbohydrate Polymers, 2022 - Elsevier
Ocular drug delivery is a significantly challenging task due to the presence of various
anatomical and physiological barriers in the eye. Naturally available polysaccharides, when …

Why chitosan could be apt candidate for glaucoma drug delivery-An overview

BN Kumara, R Shambhu, KS Prasad - International Journal of Biological …, 2021 - Elsevier
Most of the people in the world are affected by glaucoma, which leads to irreversible
blindness. Several patient friendly treatments are available, nevertheless medications lack …

Hyaluronic acid in ocular drug delivery

X Zhang, D Wei, Y Xu, Q Zhu - Carbohydrate Polymers, 2021 - Elsevier
As a naturally-occurring polysaccharide which could be found in various ophthalmic tissues,
hyaluronic acid (HA) has a wide range of applications in the eye, including treatment of dry …

[HTML][HTML] Chitosan and its derivatives for ocular delivery formulations: Recent advances and developments

A Zamboulis, S Nanaki, G Michailidou, I Koumentakou… - Polymers, 2020 - mdpi.com
Chitosan (CS) is a hemi-synthetic cationic linear polysaccharide produced by the
deacetylation of chitin. CS is non-toxic, highly biocompatible, and biodegradable, and it has …

[HTML][HTML] Polysaccharide-based nanogels and ocular drug delivery: The emerging nanocarrier for crossing blood retinal barrier

DM Modi, AD Modi - Carbohydrate Polymer Technologies and Applications, 2023 - Elsevier
The present era demands the development of drug delivery systems that can target
therapeutic agents to the site of action with minimal concentration, thereby avoiding …

Colloidal nanosystems with mucoadhesive properties designed for ocular topical delivery

B Silva, B São Braz, E Delgado, L Gonçalves - International Journal of …, 2021 - Elsevier
Over the last years, the scientific interest about topical ocular delivery targeting the posterior
segment of the eye has been increasing. This is probably due to the fact that this is a non …