Pemphigus: a comprehensive review on pathogenesis, clinical presentation and novel therapeutic approaches

R Pollmann, T Schmidt, R Eming, M Hertl - Clinical reviews in allergy & …, 2018 - Springer
Pemphigus is a group of rare, potentially devastating autoimmune diseases of the skin and
mucous membranes with high morbidity and potentially lethal outcome. The major clinical …

Autoimmune pemphigus: latest advances and emerging therapies

YL Lim, G Bohelay, S Hanakawa, P Musette… - Frontiers in Molecular …, 2022 - frontiersin.org
Pemphigus represents a group of rare and severe autoimmune intra-epidermal blistering
diseases affecting the skin and mucous membranes. These painful and debilitating diseases …

Pemphigus

M Kasperkiewicz, CT Ellebrecht, H Takahashi… - Nature reviews Disease …, 2017 - nature.com
Pemphigus is a group of IgG-mediated autoimmune diseases of stratified squamous
epithelia, such as the skin and oral mucosa, in which acantholysis (the loss of cell adhesion) …

Autoreactive T cells in the immune pathogenesis of pemphigus vulgaris

KT Amber, P Staropoli, MI Shiman… - Experimental …, 2013 - Wiley Online Library
Pemphigus vulgaris is a life‐threatening autoimmune blistering disease caused by anti‐
desmoglein I g G autoantibodies that finally lead to acantholysis presenting clinically as …

Immune response in pemphigus and beyond: progresses and emerging concepts

G Di Zenzo, KT Amber, BS Sayar, EJ Müller… - Seminars in …, 2016 - Springer
Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are two severe autoimmune bullous
diseases of the mucosae and/or skin associated with autoantibodies directed against …

Pemphigus: current and future therapeutic strategies

D Didona, R Maglie, R Eming, M Hertl - Frontiers in immunology, 2019 - frontiersin.org
Pemphigus encompasses a heterogeneous group of autoimmune blistering diseases, which
affect both mucous membranes and the skin. The disease usually runs a chronic-relapsing …

Autoimmunity against desmosomal cadherins in pemphigus

M Amagai - Journal of dermatological science, 1999 - Elsevier
Pemphigus is a unique and interesting autoimmune disease, in which autoantibodies play a
major pathogenic role and cause blister formation. Several questions raised from clinical …

Autoantibody-specific signalling in pemphigus

T Schmitt, J Waschke - Frontiers in Medicine, 2021 - frontiersin.org
Pemphigus is a severe autoimmune disease impairing barrier functions of epidermis and
mucosa. Autoantibodies primarily target the desmosomal adhesion molecules desmoglein …

Pemphigus vulgaris: update on etiopathogenesis, oral manifestations, and management

C Scully, SJ Challacombe - Critical Reviews in Oral Biology …, 2002 - journals.sagepub.com
Pemphigus is a group of potentially life-threatening diseases characterized by cutaneous
and mucosal blistering. There is a fairly strong genetic background to pemphigus with …

[HTML][HTML] Pemphigus and pemphigoid: from disease mechanisms to druggable pathways

CT Ellebrecht, D Maseda, AS Payne - Journal of Investigative Dermatology, 2022 - Elsevier
Pemphigus and pemphigoid are paradigms for understanding the mechanisms of antibody-
mediated autoimmune disease in humans. In pemphigus, IgG4-predominant autoantibodies …