Alterations of epigenetic marks are linked to normal development and cellular differentiation
as well as to the progression of common chronic diseases. The plasticity of these marks …

Dietary selenium intake is regarded as an important factor in determining optimal health and
susceptibility to disease. Therefore, it is critical to understand the interaction between …

Mechanistic data have revealed a key role for selenium (Se) and selenoproteins in
biological pathways known to be altered in multifactorial diseases, such as cellular …

Chemopreventive activity of selenium (Se) may influence epigenome. In this review, we
have discussed two aspects of Se and epigenetics in cancer, related to (1) the association …

This review traces the discoveries that led to the recognition of selenium (Se) as an essential
nutrient and discusses Se-responsive diseases in animals and humans in the context of …

This review discusses progress in understanding the hierarchy of selenoprotein expression
at the transcriptome level from selenium (Se) deficiency to Se toxicity. Microarray studies of …

Significance: Adequate and supranutritional selenium (Se) intake, maintaining full
expression of selenoproteins, has been assumed to be beneficial for human health with …

The essential trace mineral selenium is an important determinant of oxidative stress
susceptibility, with several studies showing an inverse relationship between selenium intake …

In this Special Issue of Nutrients,“The Role of Selenium in Health and Disease” covers
diverse diseases in the 8 original research articles and 2 reviews, such as cardiovascular …

Selenium (Se) is an essential micronutrient that is incorporated into selenoproteins.
Although epidemiological studies suggest that low Se intake is associated with increased …