Withdrawal of inhaled corticosteroids in COPD: a European Respiratory Society guideline

JD Chalmers, IF Laska, FME Franssen… - European …, 2020 - Eur Respiratory Soc
Inhaled corticosteroids (ICS) combined with bronchodilators can reduce the frequency of
exacerbations in some patients with chronic obstructive pulmonary disease (COPD). There …

Applying the wisdom of stepping down inhaled corticosteroids in patients with COPD: a proposed algorithm for clinical practice

AG Kaplan - … Journal of Chronic Obstructive Pulmonary Disease, 2015 - Taylor & Francis
Current guidelines for the management of chronic obstructive pulmonary disease (COPD)
recommend limiting the use of inhaled corticosteroids (ICS) to patients with more severe …

Inhaled corticosteroids in COPD: friend or foe?

A Agusti, LM Fabbri, D Singh, J Vestbo… - European …, 2018 - Eur Respiratory Soc
The efficacy, safety and positioning of inhaled corticosteroids (ICS) in the treatment of
patients with chronic obstructive pulmonary disease (COPD) is much debated, since it can …

Withdrawal of inhaled corticosteroids in individuals with COPD-a systematic review and comment on trial methodology

NJ Nadeem, SJC Taylor, SM Eldridge - Respiratory research, 2011 - Springer
Inhaled corticosteroids (ICS) reduce COPD exacerbation frequency and slow decline in
health related quality of life but have little effect on lung function, do not reduce mortality, and …

Withdrawal of inhaled corticosteroids in people with COPD in primary care: a randomised controlled trial

AB Choudhury, CM Dawson, HE Kilvington… - Respiratory …, 2007 - Springer
Background Guidelines recommend inhaled corticosteroids (ICS) for patients with severe
chronic obstructive pulmonary disease (COPD). Most COPD patients are managed in …

Withdrawal of inhaled corticosteroids can be safe in COPD patients at low risk of exacerbation: a real-life study on the appropriateness of treatment in moderate COPD …

A Rossi, M Guerriero, A Corrado - Respiratory research, 2014 - Springer
Background It has been suggested that withdrawal of inhaled corticosteroids (ICS) in COPD
patients on maintenance treatment results in deterioration of symptoms, lung function and …

Methodological issues in therapeutic trials of COPD

S Suissa, P Ernst, KL Vandemheen… - European Respiratory …, 2008 - Eur Respiratory Soc
The recent Towards a Revolution in COPD Health (TORCH) randomised trial replicated the
findings of previous trials in chronic obstructive pulmonary disease (COPD) on the apparent …

Inhaled corticosteroids in COPD: the clinical evidence

P Ernst, N Saad, S Suissa - European Respiratory Journal, 2015 - Eur Respiratory Soc
In this article, we focus on the scientific evidence from randomised trials supporting
treatment with inhaled corticosteroids (ICS) in chronic obstructive pulmonary disease …

Inhaled corticosteroids vs placebo for preventing COPD exacerbations: a systematic review and metaregression of randomized controlled trials

R Agarwal, AN Aggarwal, D Gupta, SK Jindal - Chest, 2010 - Elsevier
Background Inhaled corticosteroids (ICS) have been shown to decrease the occurrence of
COPD exacerbations. However, the relationship of baseline lung function and reduction of …

Inhaled corticosteroids for stable chronic obstructive pulmonary disease

IA Yang, MS Clarke, EHA Sim… - Cochrane Database of …, 2012 - cochranelibrary.com
Background The role of inhaled corticosteroids (ICS) in chronic obstructive pulmonary
disease (COPD) has been the subject of much controversy. Major international guidelines …