Ventilation/perfusion matching: Of myths, mice, and men

AR Clark, KS Burrowes, MH Tawhai - Physiology, 2019 - journals.physiology.org
Despite a huge range in lung size between species, there is little measured difference in the
ability of the lung to provide a well-matched air flow (ventilation) to blood flow (perfusion) at …

Comparative physiology of lung complexity: implications for gas exchange

FL Powell, SR Hopkins - Physiology, 2004 - journals.physiology.org
Lungs evolved to increase diffusing capacity by compartmentalizing and reducing the size of
individual gas exchange units. This increased the potential for gas exchange limitations from …

Gravity outweighs the contribution of structure to passive ventilation-perfusion matching in the supine adult human lung

W Kang, AR Clark, MH Tawhai - Journal of Applied …, 2018 - journals.physiology.org
Gravity and matched airway/vascular tree geometries are both hypothesized to be key
contributors to ventilation-perfusion (V̇/Q̇) matching in the lung, but their relative …

Case Studies in Physiology: Ventilation and perfusion in a giraffe–does size matter?

G Nyman, B Röken, EM Hedin… - Journal of Applied …, 2016 - journals.physiology.org
The trachea in the giraffe is long but narrow, and dead space ventilation is considered to be
of approximately the same size as in other mammals. Less is known about the matching …

The human lung: did evolution get it wrong?

JB West, RR Watson, Z Fu - European Respiratory Journal, 2007 - Eur Respiratory Soc
Some 300 million yrs ago, the ancestors of modern reptiles emerged from water and were
committed to air breathing. They were exothermic and incapable of sustained levels of high …

Unidirectional pulmonary airflow in vertebrates: a review of structure, function, and evolution

RL Cieri, CG Farmer - Journal of Comparative Physiology B, 2016 - Springer
Mechanisms explaining unidirectional pulmonary airflow in birds, a condition where lung
gases flow in a consistent direction during both inspiration and expiration in some parts of …

Comparative physiology of the pulmonary circulation

JB West - Comprehensive Physiology, 2011 - Wiley Online Library
Two selective pressures have shaped the evolution of the pulmonary circulation. First, as
animals evolved from heterothermic ectotherms to homeothermic endoderms with their …

[图书][B] Respiratory physiology: understanding gas exchange

H Prange - 2012 - books.google.com
Why write another small book on respiratory physiology? I have a dozen or so texts on my
bookshelf that could already be used interchangeably to teach the subject. For profit, I might …

Closed system respirometry may underestimate tissue gas exchange and bias the respiratory exchange ratio (RER)

CL Malte, S Nørgaard, T Wang - … and Physiology Part A: Molecular & …, 2016 - Elsevier
Closed respirometry is a commonly used method to measure gas exchange in animals due
to its apparent simplicity. Typically, the rates of O 2 uptake and CO 2 excretion (V˙ O2 and V˙ …

Interplay between optimal ventilation and gas transport in a model of the human lung

F Noël, B Mauroy - Frontiers in physiology, 2019 - frontiersin.org
Ventilation is at the origin of a spending of energy coming from air circulation in the
bronchial tree and from the mechanical resistance of the tissue to motion. Both amplitude …