Randomized, single-blind, parallel clinical trial on efficacy of oral prednisolone versus intramuscular corticotropin: a 12-month assessment of spasm control in West …

J Wanigasinghe, C Arambepola, SS Ranganathan… - Pediatric …, 2017 - Elsevier
Objective We earlier completed a single-blind, parallel-group, randomized clinical trial to test
the null hypothesis that adrenocorticotropic hormone (ACTH) is not superior to high-dose …

Randomized, single-blind, parallel clinical trial on efficacy of oral prednisolone versus intramuscular corticotropin on immediate and continued spasm control in west …

J Wanigasinghe, C Arambepola, SS Ranganathan… - Pediatric …, 2015 - Elsevier
Objective A single-center, single-blind, parallel-group, randomized clinical trial was
performed to test the null hypothesis that adrenocorticotropic hormone is not superior to high …

Corticotrophin-ACTH in comparison to prednisolone in West syndrome–A randomized Study

VK Gowda, V Narayanaswamy, SK Shivappa… - The Indian Journal of …, 2019 - Springer
Objective To compare the outcomes of adrenocorticotrophic hormone (ACTH) and
Prednisolone therapy in children with West syndrome. Methods The study was done at a …

Epilepsy outcome at four years in a randomized clinical trial comparing oral prednisolone and intramuscular ACTH in west syndrome

J Wanigasinghe, C Arambepola, SS Ranganathan… - Pediatric Neurology, 2021 - Elsevier
Background This article explores the role of initial treatment on control of spasms and other
epilepsies at four years in children previously treated for West syndrome. Methods The Sri …

Adrenocorticotropic hormone for the treatment of West Syndrome in children

NA Shumiloff, WM Lam… - Annals of …, 2013 - journals.sagepub.com
OBJECTIVE To review the current literature on the efficacy and safety of low-versus high-
dose adrenocorticotropic hormone (ACTH) regimens, low-dose ACTH regimens, and …

Therapeutic efficacy and adverse effects of adrenocorticotropic hormone therapy in west syndrome: differences in dosage of adrenocorticotropic hormone, onset of …

S Hamano, S Yamashita, M Tanaka, S Yoshinari… - The Journal of …, 2006 - Elsevier
OBJECTIVES: To determine the dosage and factors influencing efficacy of
adrenocorticotropic hormone (ACTH) for West syndrome. STUDY DESIGN: A retrospective …

The efficacy of moderate-to-high dose oral prednisolone versus low-to-moderate dose intramuscular corticotropin for improvement of hypsarrhythmia in West …

J Wanigasinghe, C Arambepola, SS Ranganathan… - Pediatric …, 2014 - Elsevier
Background The role of therapy on improvement of hypsarrhythmia has not been
systematically assessed. This study was performed to assess the efficacy of oral …

Liposteroid (dexamethasone palmitate) therapy for West syndrome: a comparative study with ACTH therapy

H Yamamoto, M Asoh, H Murakami, N Kamiyama… - Pediatric …, 1998 - Elsevier
Dexamethasone palmitate (liposteroid) was used for the treatment of West syndrome and
compared with adrenocorticotropic hormone (ACTH) therapy. A single intravenous injection …

Safety, feasibility and effectiveness of pulse methylprednisolone therapy in comparison with intramuscular adrenocorticotropic hormone in children with west …

M Rajpurohit, A Gupta, P Madaan, JK Sahu… - Indian Journal of …, 2021 - Springer
Objective To assess the feasibility, effectiveness, and safety of pulse methylprednisolone in
comparison with intramuscular adrenocorticotropic hormone (ACTH) therapy in children with …

Long-term weekly ACTH therapy for relapsed West syndrome

T Okanishi, C Sugiura, Y Saito, Y Maegaki, K Ohno… - Pediatric …, 2008 - Elsevier
Adrenocorticotrophic hormone (ACTH) therapy is an established treatment for West
syndrome. However, some patients may relapse after this therapy, for whom there is no …