Design and challenges of radiopharmaceuticals

K Vermeulen, M Vandamme, G Bormans… - Seminars in nuclear …, 2019 - Elsevier
This review describes general concepts with regard to radiopharmaceuticals for diagnostic
or therapeutic applications that help to understand the specific challenges encountered …

[图书][B] Radiopharmaceuticals for therapy

FF Knapp, A Dash - 2016 - Springer
As a foundation for a discussion of the development and use of therapeutic
radiopharmaceuticals, it is first necessary to provide an introduction to the field of nuclear …

[图书][B] Handbook of radiopharmaceuticals: radiochemistry and applications

MJ Welch, CS Redvanly - 2003 - books.google.com
A comprehensive, authoritative and up-to-date reference for the newcomer to
radiopharmaceuticals and those already in the field. Radiopharmaceuticals are used to …

[图书][B] The handbook of radiopharmaceuticals

A Owunwanne - 2012 - books.google.com
One Radiobiopharmaceutics.-1 Preparation of radiopharmaceuticals.-Production of
radionuclides.-Synthesis of the non-radioactive compound.-Reaction of the radionuclide …

Towards molecular imaging and treatment of disease with radionuclides: the role of inorganic chemistry

P Blower - Dalton Transactions, 2006 - pubs.rsc.org
Molecular imaging and radiotherapy using radionuclides is a rapidly expanding field of
medicine and medical research. This article highlights the development of the role of …

Guideline to regulations for radiopharmaceuticals in early phase clinical trials in the EU

A Verbruggen, HH Coenen, JR Deverre… - European journal of …, 2008 - Springer
The purpose of this guideline is to help investigators by giving an overview of relevant
current EU requirements concerning the quality of starting materials and final drug products …

Radionuclides for targeted therapy: physical properties

C Stokke, M Kvassheim, J Blakkisrud - Molecules, 2022 - mdpi.com
A search in PubMed revealed that 72 radionuclides have been considered for molecular or
functional targeted radionuclide therapy. As radionuclide therapies increase in number and …

Current status of radiopharmaceutical therapy

SS James, B Bednarz, S Benedict… - International Journal of …, 2021 - Elsevier
In radiopharmaceutical therapy (RPT), a radionuclide is systemically or locally delivered with
the goal of targeting and delivering radiation to cancer cells while minimizing radiation …

The chemical scaffold of theranostic radiopharmaceuticals: radionuclide, bifunctional chelator, and pharmacokinetics modifying linker

HA Holik, FM Ibrahim, AA Elaine, BD Putra, A Achmad… - Molecules, 2022 - mdpi.com
Therapeutic radiopharmaceuticals have been researched extensively in the last decade as
a result of the growing research interest in personalized medicine to improve diagnostic …

Nuclear medicine applications in molecular imaging

FG Blankenberg, HW Strauss - Journal of Magnetic Resonance …, 2002 - Wiley Online Library
With the emergence of the new field of molecular imaging, there is an increasing demand for
development of sensitive and safe novel imaging agents that can be rapidly translated from …