In clinical exome and genome sequencing, there is a potential for the recognition and
reporting of incidental or secondary findings unrelated to the indication for ordering the …

Disclaimer: These recommendations are designed primarily as an educational resource for
medical geneticists and other healthcare providers to help them provide quality medical …

Introduction The issue of incidental findings in genomics research has been contentious,
particularly in whole genome sequencing (WGS) and whole exome sequencing (WES). An …

Disclaimer: This statement is designed primarily as an educational resource for medical
geneticists and other clinicians to help them provide quality medical services. Adherence to …

ACMG SF v3.1 list for reporting of secondary findings in clinical exome and genome
sequencing: A policy statement of the American College of Medical Genetics and Genomics …

Clinicians are encouraged to document the reasons for the use of a particular procedure or
test, whether or not it is in conformance with this statement. Clinicians also are advised to …

Disclaimer: This statement is designed primarily as an educational resource for medical
geneticists and other clinicians to help them provide quality medical services. Adherence to …

Professional recommendations for the return of results from exome and whole-genome
sequencing (ES/WGS) have been controversial. The lack of clear guidance about whether …

This article characterizes the opinions of patients and family members of patients
undergoing clinical genomic-based testing regarding the return of incidental findings from …

Purpose Clinical exome sequencing is nondiagnostic for about 75% of patients evaluated
for a possible Mendelian disorder. We examined the ability of systematic reevaluation of …