Quantification of Magnetic Nanoparticles in ex vivo Colorectal Lymph Nodes

L Molenaar, MMH van de Loosdrecht, L Alic… - Nano Life, 2022 - World Scientific
En-bloc tumor resection is the standard treatment for locally advanced colorectal cancer
(CRC). An extensive histopathological assessment is necessary to evaluate the metastatic …

Ex vivo sentinel lymph node mapping in colorectal cancer using a magnetic nanoparticle tracer to improve staging accuracy: a pilot study

JJ Pouw, MR Grootendorst, JM Klaase… - Colorectal …, 2016 - Wiley Online Library
Aim Nodal status is the most important prognostic factor in colorectal cancer (CRC). Small
occult metastases may remain undetected on conventional histopathological examination …

Detection of magnetic nanoparticles for clinical interventions

M Visscher - 2014 - research.utwente.nl
In this thesis the possibilities of detection of magnetic nanoparticles for clinical interventions
are investigated. Detection of these particles in, for example, the sentinel lymph node …

Functional roles of magnetic nanoparticles for the identification of metastatic lymph nodes in cancer patients

Y Yan, Y Liu, T Li, Q Liang, A Thakur, K Zhang… - Journal of …, 2023 - Springer
Staging lymph nodes (LN) is crucial in diagnosing and treating cancer metastasis.
Biotechnologies for the specific localization of metastatic lymph nodes (MLNs) have …

Quantitative analysis of superparamagnetic contrast agent in sentinel lymph nodes using ex vivo vibrating sample magnetometry

M Visscher, JJ Pouw, J van Baarlen… - IEEE transactions on …, 2013 - ieeexplore.ieee.org
As the first step in developing a new clinical technique for the magnetic detection of
colorectal sentinel lymph nodes (SLNs), a method is developed to measure the magnetic …

Application of magnetic nanoparticles for rapid detection and in situ diagnosis in clinical oncology

T Onishi, K Mihara, S Matsuda, S Sakamoto… - Cancers, 2022 - mdpi.com
Simple Summary Screening, monitoring, and diagnostic methods in oncology are a critical
part of treatment. The currently used clinical methods have limitations, most notably the time …

Ex vivo magnetic sentinel lymph node detection in colorectal cancer with a SPIO tracer

JJ Pouw, RM Fratila, AH Velders, B ten Haken… - … Particle Imaging: A …, 2012 - Springer
A new method for selecting sentinel lymph nodes (SNs) in colorectal cancer tissue was
investigated in 12 patients. A tracer consisting of superparamagnetic ironoxide (SPIO) …

Comparison of three magnetic nanoparticle tracers for sentinel lymph node biopsy in an in vivo porcine model

JJ Pouw, M Ahmed, B Anninga… - International journal …, 2015 - Taylor & Francis
Introduction Breast cancer staging with sentinel lymph node biopsy relies on the use of
radioisotopes, which limits the availability of the procedure worldwide. The use of a …

How can nanoparticles be used in sentinel node detection?

M Ahmed, MCL Peek, M Douek - Nanomedicine, 2017 - Taylor & Francis
Editorial Ahmed, Peek & Douek the detection of axillary involvement of 98 and 96%,
respectively [10]. A limitation to implementation of this approach is the elevated false positive …

A Magnetometer Cooled with Liquid Nitrogen for the Characterization and Quantification of Magnetic Nanoparticles in Biological Samples at Room Temperature

M Visscher, M Holling, J Pouw, B Ten Haken - Magnetic Particle Imaging: A …, 2012 - Springer
For several medical applications of magnetic nanoparticles (MNP) it is desired to know the
quantity and characteristics of the particles in the tissue of interest. That can either be …