Machine learning frameworks to predict neoadjuvant chemotherapy response in breast cancer using clinical and pathological features

N Meti, K Saednia, A Lagree, S Tabbarah… - JCO Clinical Cancer …, 2021 - ascopubs.org
PURPOSE Neoadjuvant chemotherapy (NAC) is used to treat locally advanced breast
cancer (LABC) and high-risk early breast cancer (BC). Pathological complete response …

Developing a prediction model for pathologic complete response following neoadjuvant chemotherapy in breast cancer: a comparison of model building approaches

RB Basmadjian, S Kong, DJ Boyne… - JCO Clinical Cancer …, 2022 - ascopubs.org
PURPOSE The optimal characteristics among patients with breast cancer to recommend
neoadjuvant chemotherapy is an active area of clinical research. We developed and …

Multivariate machine learning models for prediction of pathologic response to neoadjuvant therapy in breast cancer using MRI features: a study using an independent …

EH Cain, A Saha, MR Harowicz, JR Marks… - Breast cancer research …, 2019 - Springer
Purpose To determine whether a multivariate machine learning-based model using
computer-extracted features of pre-treatment dynamic contrast-enhanced magnetic …

[HTML][HTML] Multimodal deep learning models for the prediction of pathologic response to neoadjuvant chemotherapy in breast cancer

S Joo, ES Ko, S Kwon, E Jeon, H Jung, JY Kim… - Scientific reports, 2021 - nature.com
The achievement of the pathologic complete response (pCR) has been considered a metric
for the success of neoadjuvant chemotherapy (NAC) and a powerful surrogate indicator of …

Predictions of the pathological response to neoadjuvant chemotherapy in patients with primary breast cancer using a data mining technique

M Takada, M Sugimoto, S Ohno, K Kuroi, N Sato… - Breast cancer research …, 2012 - Springer
Nomogram, a standard technique that utilizes multiple characteristics to predict efficacy of
treatment and likelihood of a specific status of an individual patient, has been used for …

[HTML][HTML] Novel computational biology modeling system can accurately forecast response to neoadjuvant therapy in early breast cancer

JR Peterson, JA Cole, JR Pfeiffer, GH Norris… - Breast Cancer …, 2023 - Springer
Background Generalizable population-based studies are unable to account for individual
tumor heterogeneity that contributes to variability in a patient's response to physician-chosen …

[HTML][HTML] Development and validation of a radiopathomic model for predicting pathologic complete response to neoadjuvant chemotherapy in breast cancer patients

J Zhang, Q Wu, W Yin, L Yang, B Xiao, J Wang, X Yao - BMC cancer, 2023 - Springer
Background Neoadjuvant chemotherapy (NAC) has become the standard therapeutic option
for early high-risk and locally advanced breast cancer. However, response rates to NAC vary …

Machine learning with magnetic resonance imaging for prediction of response to neoadjuvant chemotherapy in breast cancer: A systematic review and meta-analysis

X Liang, X Yu, T Gao - European Journal of Radiology, 2022 - Elsevier
Purpose The aim of this meta-analysis was to determine the diagnostic accuracy of machine
learning (ML) models with MRI in predicting pathological response to neoadjuvant …

[HTML][HTML] Deep learning prediction of pathological complete response, residual cancer burden, and progression-free survival in breast cancer patients

H Dammu, T Ren, TQ Duong - Plos one, 2023 - journals.plos.org
The goal of this study was to employ novel deep-learning convolutional-neural-network
(CNN) to predict pathological complete response (PCR), residual cancer burden (RCB), and …

Machine learning for predicting the response of breast cancer to neoadjuvant chemotherapy

S Mani, Y Chen, X Li, L Arlinghaus… - Journal of the …, 2013 - academic.oup.com
Objective To employ machine learning methods to predict the eventual therapeutic response
of breast cancer patients after a single cycle of neoadjuvant chemotherapy (NAC). Materials …