Transient hypothyroxinemia of prematurity

EF La Gamma, SJ Korzeniewski, P Ballabh… - …, 2016 - publications.aap.org
Thyroid hormones play an important role in central nervous system development, starting
from the exclusive maternal contribution in the first trimester and transitioning to a fully …

Hypothyroxinemia and prematurity

N Forghani, T Aye - NeoReviews, 2008 - publications.aap.org
The growing fetus relies on adequate thyroid hormone concentrations for normal
development, which is dependent on maternal transplacental thyroid hormone passage and …

[HTML][HTML] Neonatal thyroxine supplementation for transient hypothyroxinemia of prematurity: beneficial or detrimental?

EF La Gamma, AG van Wassenaer… - Treatments in …, 2006 - Springer
Extremely low birth-weight newborns (< 1000g) experience low levels of thyroid hormone
that vary inversely with the severity of neonatal illness and the extent of developmental …

Transient hypothyroxinemia in preterm infants: the role of cord sera thyroid hormone levels adjusted for prenatal and intrapartum factors

FLR Williams, GJ Mires, C Barnett… - The Journal of …, 2005 - academic.oup.com
Context: Transient hypothyroxinemia is common in infants less than 30 wk gestation and is
associated with neurodevelopmental deficits; it has no consensus definition. We previously …

Phase 1 trial of 4 thyroid hormone regimens for transient hypothyroxinemia in neonates of< 28 weeks' gestation

EF La Gamma, AG van Wassenaer, S Ares… - …, 2009 - publications.aap.org
BACKGROUND: Transiently low levels of thyroid hormones occur in∼ 50% of neonates
born 24–28 weeks' gestation and are associated with higher rates of cerebral palsy and …

Review shows that thyroid hormone substitution could benefit transient hypothyroxinaemia of prematurity but treatment strategies need to be clarified

A Eerdekens, L Langouche, G Van den Berghe… - Acta …, 2019 - Wiley Online Library
Aim Thyroid hormones are crucial for foetal and neonatal brain development. This paper
provides an overview of the normal role of thyroid hormones in foetal brain development and …

Does transient hypothyroxinemia cause abnormal neurodevelopment in premature infants?

N Paneth - Clinics in perinatology, 1998 - perinatology.theclinics.com
It is now established from large cohort studies that premature infants who experience
transient hypothyroxinemia in the newborn period have an increased risk of later …

Transient hypothyroxinaemia in preterm infants

FLR Williams, TJ Visser, R Hume - Early human development, 2006 - Elsevier
Thyroid hormones are required for normal development of the brain. Transient
hypothyroxinaemia is the most common thyroid dysfunction in preterm infants and is defined …

Current knowledge of transient hypothyroxinemia of prematurity: to treat or not to treat?

S Iijima - The Journal of Maternal-Fetal & Neonatal Medicine, 2019 - Taylor & Francis
Abstract Background: Thyroid hormones (THs) play a critical role in normal maturation of the
developing brain in the fetus and infant. Continuing advances in neonatal medicine have …

Levels of neonatal thyroid hormone in preterm infants and neurodevelopmental outcome at 5½ years: Millennium cohort study

C Delahunty, S Falconer, R Hume… - The Journal of …, 2010 - academic.oup.com
Context: Transient hypothyroxinemia is the commonest thyroid dysfunction of premature
infants, and recent studies have found adverse associations with neurodevelopment. The …