As reperfusion therapies have become more widely used in acute myocardial infarction
patients, ischemia-induced myocardial damage has been markedly reduced, but reperfusion …

Mitochondria are key regulators of cell fate through controlling ATP generation and
releasing pro-apoptotic factors. Cardiac ischemia/reperfusion (I/R) injury to the coronary …

Thrombolytic therapy and revascularization strategies create a complete recanalization of
the occluded epicardial coronary artery in patients with myocardial infarction (MI). However …

Despite major progress in interventional and medical treatments, myocardial infarction (MI)
and subsequent development of heart failure (HF) are still associated with high mortality …

The current standard of care for acute myocardial infarction or 'heart attack'is timely
restoration of blood flow to the ischemic region of the heart. While reperfusion is essential for …

Ischemia-reperfusion injury (IR injury), produced by initial interruption and subsequent
restoration of organ blood flow, is an important clinical dilemma accompanied by various …

Mitochondria play a critical role in maintaining cellular function by ATP production. They are
also a source of reactive oxygen species (ROS) and proapoptotic factors. The role of …

Cardiovascular disease is the most common cause of death worldwide and in particular,
ischemic heart disease holds the most considerable position. Even if it has been deeply …

Reperfusion therapy must be applied as soon as possible to attenuate the ischemic insult of
acute myocardial infarction (AMI). However reperfusion is responsible for additional …

Ischaemia/reperfusion (I/R) injury of the heart represents a major health burden mainly
associated with acute coronary syndromes. While timely coronary reperfusion has become …