[HTML] nih.gov

Translocator protein 18 kDa (TSPO): molecular sensor of brain injury and repair

MK Chen, TR Guilarte - Pharmacology & therapeutics, 2008 - Elsevier
For over 15 years, the peripheral benzodiazepine receptor (PBR), recently named
translocator protein 18 kDa (TSPO) has been studied as a biomarker of reactive gliosis and …
被引用次数：591 相关文章 所有 10 个版本
[HTML] sciencedirect.com

[HTML][HTML] Imaging neuroinflammation with TSPO: A new perspective on the cellular sources and subcellular localization

TR Guilarte, AN Rodichkin, JL McGlothan… - Pharmacology & …, 2022 - Elsevier
Abstract Translocator Protein 18 kDa (TSPO), previously named Peripheral Benzodiazepine
Receptor, is a well-validated and widely used biomarker of neuroinflammation to assess …
被引用次数：56 相关文章 所有 5 个版本
[HTML] nih.gov

Translocator protein (18 kDa) TSPO: an emerging therapeutic target in neurotrauma

V Papadopoulos, L Lecanu - Experimental neurology, 2009 - Elsevier
Traumatic brain injury (TBI) induces physical, cognitive, and psychosocial deficits that affect
millions of patients. TBI activates numerous cellular mechanisms and molecular cascades …
被引用次数：220 相关文章 所有 10 个版本
[HTML] nih.gov

Translocator protein (18 kDa)/peripheral benzodiazepine receptor specific ligands induce microglia functions consistent with an activated state

J Choi, M Ifuku, M Noda, TR Guilarte - Glia, 2011 - Wiley Online Library
In the brain, translocator protein (18 kDa)(TSPO), previously called peripheral
benzodiazepine receptor (PBR), is a glial protein that has been extensively used as a …
被引用次数：133 相关文章 所有 8 个版本
[PDF] wiley.com

The 18 kDa translocator protein, microglia and neuroinflammation

GJ Liu, RJ Middleton, CR Hatty, WWY Kam… - Brain …, 2014 - Wiley Online Library
The 18 kDa translocator protein (TSPO), previously known as the peripheral
benzodiazepine receptor, is expressed in the injured brain. It has become known as an …
被引用次数：239 相关文章 所有 10 个版本
[PDF] academia.edu

Radiolabelled molecules for imaging the translocator protein (18 kDa) using positron emission tomography

F Dollé, C Luus, A Reynolds… - Current medicinal …, 2009 - ingentaconnect.com
The translocator protein (18 kDa)(TSPO), formerly known as the peripheral benzodiazepine
receptor (PBR), was originally identified as an alternate binding site for the central …
被引用次数：138 相关文章 所有 11 个版本
[HTML] nih.gov

TSPO in diverse CNS pathologies and psychiatric disease: A critical review and a way forward

TR Guilarte - Pharmacology & therapeutics, 2019 - Elsevier
Abstract The use of Translocator Protein 18 kDa (TSPO) as a clinical neuroimaging
biomarker of brain injury and neuroinflammation has increased exponentially in the last …
被引用次数：144 相关文章 所有 6 个版本
[HTML] nih.gov

[HTML][HTML] Translocator protein (TSPO): the new story of the old protein in neuroinflammation

Y Lee, Y Park, H Nam, JW Lee, SW Yu - BMB reports, 2020 - ncbi.nlm.nih.gov
Translocator protein (TSPO), also known as peripheral benzodiazepine receptor, is a
transmembrane protein located on the outer mitochondria membrane (OMM) and mainly …
被引用次数：95 相关文章 所有 14 个版本
[PDF] mdpi.com

TSPO: an evolutionarily conserved protein with elusive functions

F Bonsack, S Sukumari-Ramesh - International journal of molecular …, 2018 - mdpi.com
TSPO (18 kDa translocator protein) was identified decades ago in a search for peripheral
tissue binding sites for benzodiazepines, and was formerly called the peripheral …
被引用次数：89 相关文章 所有 12 个版本

An update into the medicinal chemistry of translocator protein (TSPO) ligands

E Barresi, M Robello, B Costa, E Da Pozzo… - European Journal of …, 2021 - Elsevier
Abstract The Translocator Protein 18 kDa (TSPO) has been discovered in 1977 as an
alternative binding site for the benzodiazepine diazepam. It is an evolutionary well …
被引用次数：41 相关文章 所有 5 个版本