Normal pregnancy is associated with marked hemodynamic and uterine changes that allow
adequate uteroplacental blood flow and uterine expansion for the growing fetus. These …

Preeclampsia is a severe pregnancy complication globally, characterized by poor
placentation triggering vascular dysfunction. Matrix metalloproteinases (MMPs) exhibit …

Objective: We have recently demonstrated that matrix metalloproteinase-2 (MMP-2) alters
vascular function through cleavage of vasoactive peptides, resulting in increased …

The objective of this article is to review the role of matrix metalloproteinases (MMPs) in
fetomaternal/neonatal complications of preterm birth. The function of MMPs as proteolytic …

Preeclampsia is an important syndrome complicating pregnancy. While the pathogenesis of
preeclampsia is not entirely known, poor placental perfusion leading to widespread …

Gelatinases (matrix metalloproteinase-2 and-9) are enzymes from the matrix
metalloproteinases (MMPs) family, which are associated with collagen degradation. MMP-2 …

Preeclampsia is a complication of pregnancy manifested as maternal hypertension and
often fetal growth restriction. Placental ischemia could be an initiating event, but the linking …

Matrix metalloproteinases (MMPs) are a family of zinc and calcium‐dependent
endopeptidases involved in remodeling and physiological homeostasis of extracellular …

Pregnancy is associated with uteroplacental and vascular remodeling in order to adapt for
the growing fetus and the hemodynamic changes in the maternal circulation. We have …

Normal pregnancy involves extensive remodeling of uterine and spiral arteries and matrix
metalloproteinases (MMPs)-mediated proteolysis of extracellular matrix (ECM) …