Aging is the strongest risk factor for metabolic, vascular and neurodegenerative diseases.
Aging alone is associated with a gradual decline of cognitive and motor functions …

In the central nervous system (CNS), glial cells, such as microglia and astrocytes, are
normally associated with support roles including contributions to energy metabolism …

By 2050, the aging population is predicted to expand by over 100%. Considering this rapid
growth, and the additional strain it will place on healthcare resources because of age …

Gene expression studies suggest that aging of the human brain is determined by a complex
interplay of molecular events, although both its region-and cell-type-specific consequences …

The past decade or so has witnessed a rekindling of interest in glia requiring a re-evaluation
of the early descriptions of astrocytes as merely support cells, and microglia as adopting …

Astrocytes, one of the largest glial cell population in the central nervous system (CNS), play
a key function in several events of brain development and function, such as synapse …

Alzheimer's disease is a progressive, incurable neurodegenerative disease targeting
specific neuronal populations within the brain while neighboring neurons appear unaffected …

A rapidly ageing population and a limited therapeutic toolbox urgently necessitate new
approaches to treat neurodegenerative diseases. Brain ageing, the key risk factor for …

Aging brains undergo cognitive decline, associated with decreased neuronal synapse
number and function and altered metabolism. Astrocytes regulate neuronal synapse …

Glial cells and their association with neurones are fundamental for brain function. The
emergence of complex neurone-glial networks assures rapid information transfer, creating a …