Rationale: The relevance of hormones in idiopathic pulmonary fibrosis (IPF), a
predominantly male lung disease, is unknown. Objectives: To determine whether the ER …

Background Idiopathic pulmonary fibrosis (IPF) is progressive and rapidly fatal. Improved
understanding of pathogenesis is required to prosper novel therapeutics. Epigenetic …

In this review, we describe the recent advances in the understanding of the role of
microRNAs in idiopathic pulmonary fibrosis (IPF), a chronic progressive and lethal fibrotic …

Rationale: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and usually lethal
fibrotic lung disease characterized by profound changes in epithelial cell phenotype and …

Background Sex differences in idiopathic pulmonary fibrosis (IPF) suggest a protective role
for estrogen (E2); however, mechanistic studies in animal models have produced mixed …

Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease. The pathogenesis of
IPF is not completely understood. However, numerous genes are associated with the …

Pulmonary fibrosis is a pathological condition in which lungs become scarred due to the
excess extracellular matrix (ECM) deposition and structural alterations in the interstitium of …

In this study, we explored the regulation and the role of up-regulated microRNAs in
idiopathic pulmonary fibrosis (IPF), a progressive interstitial lung disease of unknown origin …

Rationale: Idiopathic pulmonary fibrosis (IPF) is a disease of progressive lung fibrosis with a
high mortality rate. In organ repair and remodeling, epigenetic events are important …

Estrogen receptor β (ERβ) is highly expressed in both type I and II pneumocytes as well as
bronchiolar epithelial cells. ERα is not detectable in the adult lung. Lungs of adult female …