Ionizing radiation is a proven human carcinogen and cataractogen. The crystalline lens of
the eye is among the most radiosensitive tissues in the body. A clouding of the normally …

We recently reported, in a series of patients receiving total body irradiation before transplant,
an influence of dose rate (DR) on cataract formation. The aim of our present in vitro study …

Epidemiological and experimental studies have revealed that exposure to UV can induce
cataractogenesis. To investigate the mechanism of this induction, viability of the lens …

Purpose This study was directed to assess the DNA damage and DNA repair response to X-
ray inflicted lens oxidative damage and to investigate the subsequent changes in lens …

Over the past century, ionizing radiation has been known to induce cataracts in the
crystalline lens of the eye, but its mechanistic underpinnings remain incompletely …

The lens of the eye has long been considered as a radiosensitive tissue, but recent research
has suggested that the radiosensitivity is even greater than previously thought. The 2012 …

The lens of the eye is one of the most radiosensitive tissues. Although the exact mechanism
of radiation-induced cataract development remains unknown, altered proliferation …

In view of renewed interest in the lens epithelium as the initiation site for cataract
development, it seemed timely to review recent studies which appear to establish UV …

The influence of dose rate on radiation cataractogenesis has yet to be extensively studied.
One recent epidemiological investigation suggested that protracted radiation exposure …

Damage to lens epithelial cells is a probable initiation process in cataract formation
mediated by UV radiation. In these experiments, we investigated the effects of exposure to …