Fibrocytes: emerging effector cells in chronic inflammation

RA Reilkoff, R Bucala, EL Herzog - Nature Reviews Immunology, 2011 - nature.com
Fibrocytes are mesenchymal cells that arise from monocyte precursors. They are present in
injured organs and have both the inflammatory features of macrophages and the tissue …

Fibrocytes: emerging effector cells in chronic inflammation

H Peng, EL Herzog - Current opinion in pharmacology, 2012 - Elsevier
Fibrocytes are unique cells possessing the proinflammatory properties of macrophages and
the tissue remodeling properties of fibroblasts. Because these cells display a strong …

[HTML][HTML] Fibrocytes in health and disease

EL Herzog, R Bucala - Experimental hematology, 2010 - Elsevier
Fibrocytes are circulating mesenchymal progenitor cells that participate in tissue responses
to injury and invasion. Accumulating knowledge from animal models regarding the …

Peripheral blood fibrocytes: mesenchymal precursor cells and the pathogenesis of fibrosis

J Chesney, R Bucala - Current rheumatology reports, 2000 - Springer
Peripheral blood fibrocytes are a novel population of cells that rapidly enter sites of tissue
injury and contribute to connective scar formation. Fibrocytes display a distinct cell surface …

The role of circulating fibrocytes in fibrosis

TE Quan, SE Cowper, R Bucala - Current rheumatology reports, 2006 - Springer
Fibrocytes are cells that circulate in the peripheral blood and produce connective tissue
proteins such as vimentin and collagens I and III. Fibrocytes are associated with skin lesions …

Fibrocytes: a unique cell population implicated in wound healing

CN Metz - Cellular and Molecular Life Sciences CMLS, 2003 - Springer
Following tissue damage, host wound healing ensues. This process requires an elaborate
interplay between numerous cell types which orchestrate a series of regulated and …

Fibrocytes: bringing new insights into mechanisms of inflammation and fibrosis

EC Keeley, B Mehrad, RM Strieter - … journal of biochemistry & cell biology, 2010 - Elsevier
Regeneration and fibrosis are integral parts of the recovery process following tissue injury,
and impaired regulation of these mechanisms is a hallmark of many chronic diseases. A …

Fibrocytes in lung disease

BN Gomperts, RM Strieter - Journal of Leucocyte Biology, 2007 - academic.oup.com
Fibrocytes were first described over a decade ago as a population of cells in circulation with
fibroblast-like properties, which were involved in tissue repair. Since that time, we have …

Circulating fibrocytes: collagen-secreting cells of the peripheral blood

TE Quan, S Cowper, SP Wu, LK Bockenstedt… - The international journal …, 2004 - Elsevier
Since the original description of circulating fibrocytes in 1994, our knowledge of this unique
cell population has grown steadily. While initially described in the context of wound repair …

[HTML][HTML] The role of fibrocytes in fibrotic diseases of the lungs and heart

EC Keeley, B Mehrad, RM Strieter - Fibrogenesis & tissue repair, 2011 - Springer
Fibrosis is the end result of a complex series of events that follow tissue injury and
inflammation. Pathophysiologic fibrosis results in permanent scar formation, and can impair …