[PDF][PDF] Estudio comparativo de diferentes inductores de autofagia en un modelo in vivo de la enfermedad de Parkinson y su influencia sobre la microbiota intestinal

Y Gopar Cuevas - 2023 - eprints.uanl.mx
Since the number of aged people will increase in the next years, neurodegenerative
diseases, including Parkinson's Disease (PD), will also rise. Previously, we demonstrated …

Metformin and Trehalose-Modulated Autophagy Exerts a Neurotherapeutic Effect on Parkinsonʼs Disease

Y Gopar-Cuevas, O Saucedo-Cardenas… - Molecular …, 2023 - Springer
Since the number of aged people will increase in the next years, neurodegenerative
diseases, including Parkinson's Disease (PD), will also rise. Recently, we demonstrated that …

Colonic dopaminergic neurons changed reversely with those in the midbrain via gut microbiota-mediated autophagy in a chronic Parkinson's disease mice model

X Liu, ZR Du, X Wang, KH Luk, CH Chan… - Frontiers in aging …, 2021 - frontiersin.org
The role of gut-brain axis in the pathogenesis of Parkinson's disease (PD) have become a
research hotspot, appropriate animal model to study gut-brain axis in PD is yet to be …

Autophagy stimulation decreases dopaminergic neuronal death mediated by oxidative stress

MJ Ramirez-Moreno, AP Duarte-Jurado… - Molecular …, 2019 - Springer
The neurodegenerative process of Parkinson's disease (PD) involves autophagy impairment
and oxidative stress. Therefore, we wanted to determine whether stimulation of autophagy …

Lactate and pyruvate activate autophagy and mitophagy that protect cells in toxic model of Parkinson's disease

EI Fedotova, LP Dolgacheva, AY Abramov… - Molecular …, 2022 - Springer
Intracellular quality control regulated by autophagy process is important for maintenance of
cellular homeostasis. Deregulation of autophagy and more specifically mitophagy leads to …

Nutraceuticals as modulators of autophagy: relevance in parkinson's disease

M Rakowski, S Porębski, A Grzelak - International journal of molecular …, 2022 - mdpi.com
Dietary supplements and nutraceuticals have entered the mainstream. Especially in the
media, they are strongly advertised as safe and even recommended for certain diseases …

MitoPark transgenic mouse model recapitulates the gastrointestinal dysfunction and gut-microbiome changes of Parkinson's disease

S Ghaisas, MR Langley, BN Palanisamy, S Dutta… - Neurotoxicology, 2019 - Elsevier
Gastrointestinal (GI) disturbances are one of the earliest symptoms affecting most patients
with Parkinson's disease (PD). In many cases, these symptoms are observed years before …

The gut-brain connection in the pathogenicity of Parkinson disease: putative role of autophagy

V Kakoty, KC Sarathlal, SK Dubey, CH Yang… - Neuroscience …, 2021 - Elsevier
Parkinson disease (PD) is a progressive movement functionality disorder resulting in tremor
and inability to execute voluntary functions combined with the preponderant non-motor …

Identifying Probiotics that Modulate Mitophagy in Models of Mitochondrial Dysfunction

J Gao - 2023 - search.proquest.com
Disruption of mitophagy in neurons is linked to Parkinson disease (PD), which is a
multifactorial neurodegenerative disorder that currently has no cure. The neuroprotective …

Lactulose and melibiose attenuate MPTP-induced Parkinson's disease in mice by inhibition of oxidative stress, reduction of neuroinflammation and up-regulation of …

CH Lin, PC Wei, CM Chen, YT Huang, JL Lin… - Frontiers in Aging …, 2020 - frontiersin.org
Parkinson's disease (PD) is a common neurodegenerative disease characterized by the
progressive loss of dopaminergic (DAergic) neurons in the ventral brain. A disaccharide …