[PDF][PDF] WHO technical brief: preventing HIV during pregnancy and breastfeeding in the context of PrEP

World Health Organization - 2017 - apps.who.int
In many countries with high-prevalence generalized HIV epidemics, women continue to
acquire HIV during pregnancy and breastfeeding. Women who become infected during this …

Delivering preexposure prophylaxis to pregnant and breastfeeding women in Sub-Saharan Africa: the implementation science frontier

DLJ Davey, LG Bekker, PM Gorbach, TJ Coates… - AIDS, 2017 - journals.lww.com
HIV acquisition during pregnancy and postpartum periods remains high despite increased
access to and initiation of antiretroviral therapy (ART) in Sub-Saharan Africa [1–5]. There are …

Global and national guidance for the use of pre-exposure prophylaxis during peri-conception, pregnancy and breastfeeding

N Davies, R Heffron - Sexual health, 2018 - CSIRO Publishing
Pre-exposure prophylaxis (PrEP) is a well-established biomedical HIV prevention strategy
and recommended to reduce HIV risk during peri-conception, pregnancy and breastfeeding …

Emerging evidence from a systematic review of safety of pre‐exposure prophylaxis for pregnant and postpartum women: where are we now and where are we …

DL Joseph Davey, J Pintye, JM Baeten… - Journal of the …, 2020 - Wiley Online Library
Introduction HIV incidence is high during pregnancy and breastfeeding with HIV acquisition
risk more than doubling during pregnancy and the postpartum period compared to when …

[HTML][HTML] Safety surveillance for PrEP in pregnant and breastfeeding women

L Fairlie, D Lavies, E Kalk, O Mhlongo… - … in Reproductive Health, 2023 - frontiersin.org
The risk of HIV acquisition is higher during pregnancy and postpartum than other times.
Newly acquired maternal HIV infection associated with high primary viraemia, substantially …

Where are the pregnant and breastfeeding women in new pre-exposure prophylaxis trials? The imperative to overcome the evidence gap

DLJ Davey, LG Bekker, EA Bukusi, BH Chi… - The lancet HIV, 2022 - thelancet.com
Pregnant and breastfeeding populations are at substantial risk of acquiring HIV in some
settings, yet are underrepresented in clinical trials of new pre-exposure prophylaxis (PrEP) …

[HTML][HTML] Perinatal outcomes associated with pre-exposure prophylaxis for HIV prevention during pregnancy: a systematic review and meta-analysis

A Erlwanger, I Rocroi, S Kirtley, J Hemelaar - Eclinicalmedicine, 2024 - thelancet.com
Summary Background The World Health Organization (WHO) recommends tenofovir
disoproxil fumarate (TDF)-based oral pre-exposure prophylaxis (PrEP), the dapivirine …

Modelling the potential impact of providing preexposure prophylaxis in pregnant and breastfeeding women in South Africa

DLJ Davey, LG Bekker, Y Gomba, T Coates, L Myer… - Aids, 2019 - journals.lww.com
Objective: HIV-uninfected pregnant and breastfeeding women are at high risk of HIV
acquisition, contributing to vertical transmission of HIV. Preexposure prophylaxis (PrEP) is …

Awareness, acceptability, and intention to initiate HIV pre-exposure prophylaxis among pregnant women

RK Scott, SJ Hull, RC Richards, K Klemmer… - AIDS care, 2022 - Taylor & Francis
ABSTRACT HIV prevention is critically important during pregnancy, however, pre-exposure
prophylaxis (PrEP) is underutilized. We conducted a survey of pregnant and non-pregnant …

[HTML][HTML] Pre-exposure prophylaxis use by breastfeeding HIV-uninfected women: a prospective short-term study of antiretroviral excretion in breast milk and infant …

KK Mugwanya, CW Hendrix, NR Mugo… - PLoS …, 2016 - journals.plos.org
Background As pre-exposure prophylaxis (PrEP) becomes more widely used in
heterosexual populations, an important consideration is its safety in infants who are …