The inhibition of enterocyte proliferation by lithocholic acid exacerbates necrotizing enterocolitis through downregulating the Wnt/β‐catenin signalling pathway
Z Feng, C Jia, X Lin, H Hao, S Li, F Li, Q Cui… - Cell …, 2022 - Wiley Online Library
Objectives Necrotizing enterocolitis (NEC) is a catastrophic gastrointestinal emergency in
preterm infants, whose exact aetiology remains unknown. The role of lithocholic acid (LCA) …
preterm infants, whose exact aetiology remains unknown. The role of lithocholic acid (LCA) …
Bile acids induce ileal damage during experimental necrotizing enterocolitis
MD Halpern, H Holubec, TA Saunders, K Dvorak… - Gastroenterology, 2006 - Elsevier
Background & Aims: Necrotizing enterocolitis (NEC) is the most common gastrointestinal
emergency of premature infants. While the effect of bile acids (BAs) on intestinal mucosal …
emergency of premature infants. While the effect of bile acids (BAs) on intestinal mucosal …
Potential role of bile acids in the pathogenesis of necrotizing enterocolitis
J Yang, X Chen, T Liu, Y Shi - Life Sciences, 2023 - Elsevier
Necrotizing enterocolitis (NEC) is one of the most common acute gastrointestinal diseases in
preterm infants. Recent studies have found that NEC is not only caused by changes in the …
preterm infants. Recent studies have found that NEC is not only caused by changes in the …
Taurohyodeoxycholic acid alleviates trinitrobenzene sulfonic acid induced ulcerative colitis via regulating Th1/Th2 and Th17/Treg cells balance
L Lv, Z Chen, W Bai, J Hao, Z Heng, C Meng, L Wang… - Life Sciences, 2023 - Elsevier
Aims Taurohyodeoxycholic acid (THDCA), a natural 6α-hydroxylated bile acid, exhibits
intestinal anti-inflammatory effects. This study aimed to explore the efficacy of THDCA on …
intestinal anti-inflammatory effects. This study aimed to explore the efficacy of THDCA on …
TUDCA attenuates intestinal injury and inhibits endoplasmic reticulum stress-mediated intestinal cell apoptosis in necrotizing enterocolitis
P Li, D Fu, Q Sheng, S Yu, X Bao, Z Lv - International …, 2019 - Elsevier
Neonatal necrotizing enterocolitis (NEC) is a life-threatening disease with severe
inflammation and intestinal cell apoptosis. Tauroursodeoxycholic acid (TUDCA) is a …
inflammation and intestinal cell apoptosis. Tauroursodeoxycholic acid (TUDCA) is a …
Toll-like receptor-4 inhibits enterocyte proliferation via impaired β-catenin signaling in necrotizing enterocolitis
CP Sodhi, XH Shi, WM Richardson, ZS Grant… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Necrotizing enterocolitis (NEC), the leading cause of
gastrointestinal death from gastrointestinal disease in preterm infants, is characterized by …
gastrointestinal death from gastrointestinal disease in preterm infants, is characterized by …
Gallic acid improved inflammation via NF-κB pathway in TNBS-induced ulcerative colitis
L Zhu, PQ Gu, H Shen - International immunopharmacology, 2019 - Elsevier
Gallic acid (GA), as an active component, has been found in many fruits and plants, and it
exhibits potential protective effects, such as anti-inflammatory, antioxidant, antiviral and …
exhibits potential protective effects, such as anti-inflammatory, antioxidant, antiviral and …
[HTML][HTML] Lactobacillus GG regulates the Wnt/β-catenin pathway to reinforce intestinal barrier function and alleviate necrotizing enterocolitis
Y Li, J Chen, D Sun, J Liu, Z Wang, A Li - Journal of Functional Foods, 2022 - Elsevier
Intestinal barrier function and intestinal flora imbalance lead to neonatal necrotizing
enterocolitis (NEC). Lactobacillus rhamnosus GG (LGG) has been used to prevent or treat …
enterocolitis (NEC). Lactobacillus rhamnosus GG (LGG) has been used to prevent or treat …
Carnosic acid prevents dextran sulfate sodium-induced acute colitis associated with the regulation of the Keap1/Nrf2 pathway
N Yang, Z Xia, N Shao, B Li, L Xue, Y Peng, F Zhi… - Scientific Reports, 2017 - nature.com
Crohn's disease and ulcerative colitis are inflammatory bowel diseases (IBDs) with high
prevalence in humans. Carnosic acid (CA) has been reported to possess antioxidative …
prevalence in humans. Carnosic acid (CA) has been reported to possess antioxidative …
[HTML][HTML] Echinacoside alleviated LPS-induced cell apoptosis and inflammation in rat intestine epithelial cells by inhibiting the mTOR/STAT3 pathway
L Li, G Wan, B Han, Z Zhang - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Inflammatory bowel disease (IBD) is a chronic and progressive inflammatory condition of
colon and small intestine. Echinacoside (ECH) is a phenylethanoid glycoside that …
colon and small intestine. Echinacoside (ECH) is a phenylethanoid glycoside that …
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