Loss of CRB2 in Müller glial cells modifies a CRB1-associated retinitis pigmentosa phenotype into a Leber congenital amaurosis phenotype
PM Quinn, AA Mulder, C Henrique Alves… - Human Molecular …, 2019 - academic.oup.com
Variations in the human Crumbs homolog-1 (CRB1) gene lead to an array of retinal
dystrophies including early onset of retinitis pigmentosa (RP) and Leber congenital …
dystrophies including early onset of retinitis pigmentosa (RP) and Leber congenital …
CRB2 loss in rod photoreceptors is associated with progressive loss of retinal contrast sensitivity
Variations in the Crumbs homolog-1 (CRB1) gene are associated with a wide variety of
autosomal recessive retinal dystrophies, including early onset retinitis pigmentosa (RP) and …
autosomal recessive retinal dystrophies, including early onset retinitis pigmentosa (RP) and …
Pals1/Mpp5 is required for correct localization of Crb1 at the subapical region in polarized Müller glia cells
AGSH van Rossum, WM Aartsen… - Human molecular …, 2006 - academic.oup.com
Mutations in the human Crumbs homologue-1 (CRB1) gene cause retinal diseases
including Leber's congenital amaurosis (LCA) and retinitis pigmentosa type 12. The CRB1 …
including Leber's congenital amaurosis (LCA) and retinitis pigmentosa type 12. The CRB1 …
Targeted ablation of Crb2 in photoreceptor cells induces retinitis pigmentosa
CH Alves, LP Pellissier, RM Vos… - Human molecular …, 2014 - academic.oup.com
In humans, the Crumbs homolog-1 (CRB1) gene is mutated in autosomal recessive Leber
congenital amaurosis and early-onset retinitis pigmentosa. In mammals, the Crumbs family …
congenital amaurosis and early-onset retinitis pigmentosa. In mammals, the Crumbs family …
CRB2 in immature photoreceptors determines the superior-inferior symmetry of the developing retina to maintain retinal structure and function
The mammalian apical-basal determinant Crumbs homolog-1 (CRB1) plays a crucial role in
retinal structure and function by the maintenance of adherens junctions between …
retinal structure and function by the maintenance of adherens junctions between …
Crb1 is a determinant of retinal apical Müller glia cell features
SA Van de Pavert, AS Sanz, WM Aartsen, RM Vos… - Glia, 2007 - Wiley Online Library
Mutations in the human Crumbs homologue-1 (CRB1) gene cause retinal blinding diseases,
such as Leber congenital amaurosis and retinitis pigmentosa. In the previous studies we …
such as Leber congenital amaurosis and retinitis pigmentosa. In the previous studies we …
Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene
CH Alves, A Sanz Sanz, B Park… - Human molecular …, 2013 - academic.oup.com
In humans, the Crumbs homolog-1 (CRB1) gene is mutated in progressive types of
autosomal recessive retinitis pigmentosa and Leber congenital amaurosis. However, there …
autosomal recessive retinitis pigmentosa and Leber congenital amaurosis. However, there …
Towards understanding CRUMBS function in retinal dystrophies
M Richard, R Roepman, WM Aartsen… - Human molecular …, 2006 - academic.oup.com
Mutations in the Crumbs homologue 1 (CRB1) gene cause autosomal recessive retinitis
pigmentosa (arRP) and autosomal Leber congenital amaurosis (arLCA). The crumbs (crb) …
pigmentosa (arRP) and autosomal Leber congenital amaurosis (arLCA). The crumbs (crb) …
[PDF][PDF] Characterization of the Crumbs homolog 2 (CRB2) gene and analysis of its role in retinitis pigmentosa and Leber congenital amaurosis.
JAJM van den Hurk, P Rashbass, R Roepman, J Davis… - 2005 - repository.ubn.ru.nl
PURPOSE: Mutations in the Crumbs homolog 1 (CRB1) gene cause autosomal recessive
retinitis pigmentosa (RP) and Leber congenital amaurosis (LCA). Database searches reveal …
retinitis pigmentosa (RP) and Leber congenital amaurosis (LCA). Database searches reveal …
Microarray and morphological analysis of early postnatal CRB2 mutant retinas on a pure C57BL/6J genetic background
CH Alves, K Bossers, RM Vos, AHW Essing… - PLoS …, 2013 - journals.plos.org
In humans, the Crumbs homologue-1 (CRB1) gene is mutated in progressive types of
autosomal recessive retinitis pigmentosa and Leber congenital amaurosis. The severity of …
autosomal recessive retinitis pigmentosa and Leber congenital amaurosis. The severity of …