PRECLINICAL STUDY: Ghrelin stimulates locomotor activity and accumbal dopamine‐overflow via central cholinergic systems in mice: implications for its involvement …

E Jerlhag, E Egecioglu, SL Dickson… - Addiction …, 2006 - Wiley Online Library
It is becoming increasingly apparent that there is a degree of neurochemical overlap
between the reward systems and those regulating energy balance. We therefore …

Preclinical study: ghrelin administration into tegmental areas stimulates locomotor activity and increases extracellular concentration of dopamine in the nucleus …

E Jerlhag, E Egecioglu, SL Dickson… - Addiction …, 2007 - Wiley Online Library
Ghrelin stimulates appetite, increases food intake and causes adiposity by mechanisms that
include direct actions on the brain. Previously, we showed that intracerebroventricular …

[HTML][HTML] Concomitant release of ventral tegmental acetylcholine and accumbal dopamine by ghrelin in rats

E Jerlhag, AC Janson, S Waters, JA Engel - PloS one, 2012 - journals.plos.org
Ghrelin, an orexigenic peptide, regulates energy balance specifically via hypothalamic
circuits. Growing evidence suggest that ghrelin increases the incentive value of motivated …

PRECLINICAL STUDY: systemic administration of ghrelin induces conditioned place preference and stimulates accumbal dopamine

E Jerlhag - Addiction biology, 2008 - Wiley Online Library
Ghrelin, preferably via hypothalamic circuits, is known to play a role in the control of energy
balance, body weight homeostasis and appetite. In addition, it has recently been found that …

Ghrelin induces feeding in the mesolimbic reward pathway between the ventral tegmental area and the nucleus accumbens

AM Naleid, MK Grace, DE Cummings, AS Levine - Peptides, 2005 - Elsevier
Ghrelin, a powerful orexigenic peptide released from the gut, stimulates feeding when
injected centrally and has thus far been implicated in regulation of metabolic, rather than …

Systemic administration of ghrelin increases extracellular dopamine in the shell but not the core subdivision of the nucleus accumbens

D Quarta, C Di Francesco, S Melotto… - Neurochemistry …, 2009 - Elsevier
The gut-hormone ghrelin endogenously binds to the ghrelin receptor (GHS-R) to promote
foraging and feeding behaviours mainly via the hypothalamic arcuate nucleus (ARC). GHS …

PRECLINICAL STUDY: FULL ARTICLE: Ghrelin increases intake of rewarding food in rodents

E Egecioglu, E Jerlhag, N Salomé… - Addiction …, 2010 - Wiley Online Library
We investigated whether ghrelin action at the level of the ventral tegmental area (VTA), a key
node in the mesolimbic reward system, is important for the rewarding and motivational …

[HTML][HTML] Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite

A Abizaid, ZW Liu, ZB Andrews… - The Journal of …, 2006 - Am Soc Clin Investig
The gut hormone ghrelin targets the brain to promote food intake and adiposity. The ghrelin
receptor growth hormone secretagogue 1 receptor (GHSR) is present in hypothalamic …

PRECLINICAL STUDY: Correlation between serum ghrelin levels and cocaine‐seeking behaviour triggered by cocaine‐associated conditioned stimuli in rats

M Tessari, A Catalano, M Pellitteri… - Addiction …, 2007 - Wiley Online Library
Ghrelin is a brain–gut peptide with growth hormone‐releasing and appetite‐inducing
activities. A growing body of evidence suggests that ghrelin may affect the central reward …

Ghrelin and dopamine: new insights on the peripheral regulation of appetite

A Abizaid - Journal of neuroendocrinology, 2009 - Wiley Online Library
A review is provided of current evidence supporting the actions of the stomach‐derived
peptide ghrelin on ventral tegmental area (VTA) dopamine cells to increase food intake and …