Ventral Striatal D2/3 Receptor Availability Is Associated with Impulsive Choice Behavior As Well As Limbic Corticostriatal Connectivity

RL Barlow, M Gorges, A Wearn… - International Journal …, 2018 - academic.oup.com
Background Low dopamine D2/3 receptor availability in the nucleus accumbens shell is
associated with highly impulsive behavior in rats as measured by premature responses in a …

Dopamine D2/3 Receptor Availabilities and Evoked Dopamine Release in Striatum Differentially Predict Impulsivity and Novelty Preference in Roman High- and Low …

L Bellés, A Dimiziani, S Tsartsalis… - International Journal …, 2021 - academic.oup.com
Background Impulsivity and novelty preference are both associated with an increased
propensity to develop addiction-like behaviors, but their relationship and respective …

Dopamine D2/3 receptor availability and human cognitive impulsivity: a high-resolution positron emission tomography imaging study with [11C] raclopride

JH Kim, YD Son, HK Kim, SY Lee, YB Kim… - Acta …, 2014 - cambridge.org
ObjectiveHuman impulsivity is a complex multidimensional construct encompassing
cognitive, emotional, and behavioural aspects. Previous animal studies have suggested that …

Striatal dopamine D2/D3 receptors mediate response inhibition and related activity in frontostriatal neural circuitry in humans

DG Ghahremani, B Lee, CL Robertson… - Journal of …, 2012 - Soc Neuroscience
Impulsive behavior is thought to reflect a traitlike characteristic that can have broad
consequences for an individual's success and well-being, but its neurobiological basis …

Prefrontal cortical–striatal dopamine receptor m RNA expression predicts distinct forms of impulsivity

NW Simon, BS Beas, KS Montgomery… - European Journal of …, 2013 - Wiley Online Library
Variation in dopamine receptor levels has been associated with different facets of
impulsivity. To further delineate the neural substrates underlying impulsive action (inability to …

Ventral tegmental area D2 receptor knockdown enhances choice impulsivity in a delay-discounting task in rats

KA Bernosky-Smith, YY Qiu, M Feja, YB Lee… - Behavioural brain …, 2018 - Elsevier
Impulsivity associated with abnormal dopamine (DA) function has been observed in several
disorders, including addiction. Choice impulsivity is the preference for small, immediate …

High impulsive choice is accompanied by an increase in dopamine release in rat dorsolateral striatum

M Moreno, V Azocar, A Vergés… - Behavioural Brain …, 2021 - Elsevier
Dopamine neurotransmission has been consistently associated with individual differences
in impulsive choice. Clinical and preclinical evidence suggests that low striatal dopamine D …

[HTML][HTML] Dissociable rate-dependent effects of oral methylphenidate on impulsivity and D2/3 receptor availability in the striatum

D Caprioli, B Jupp, YT Hong, SJ Sawiak… - Journal of …, 2015 - Soc Neuroscience
We have previously shown that impulsivity in rats is linked to decreased dopamine D 2/3
receptor availability in the ventral striatum. In the present study, we investigated, using …

Human brain imaging links dopaminergic systems to impulsivity

ED London - Recent Advances in Research on Impulsivity and …, 2020 - Springer
Molecular and functional imaging techniques have been used and combined with
pharmacological probes to evaluate the role of dopamine in impulsivity. Overall, strong …

Dissociable control of impulsivity in rats by dopamine d2/3 receptors in the core and shell subregions of the nucleus accumbens

M Besson, D Belin, R McNamara… - …, 2010 - nature.com
Previous research has identified the nucleus accumbens (NAcb) as an important brain
region underlying inter-individual variation in impulsive behavior. Such variation has been …