[HTML][HTML] Amino acids and their transporters in T cell immunity and cancer therapy

W Wang, W Zou - Molecular cell, 2020 - cell.com
Metabolism reprogramming is critical for both cancer progression and effective immune
responses in the tumor microenvironment. Amino acid metabolism in different cells and their …

[HTML][HTML] Amino acid metabolism in immune cells: essential regulators of the effector functions, and promising opportunities to enhance cancer immunotherapy

L Yang, Z Chu, M Liu, Q Zou, J Li, Q Liu… - Journal of hematology & …, 2023 - Springer
Amino acids are basic nutrients for immune cells during organ development, tissue
homeostasis, and the immune response. Regarding metabolic reprogramming in the tumor …

Fueling T-cell antitumor immunity: amino acid metabolism revisited

C Han, M Ge, PC Ho, L Zhang - Cancer immunology research, 2021 - AACR
T cells are the key players in eliminating malignant tumors. Adoptive transfer of tumor
antigen-specific T cells and immune checkpoint blockade has yielded durable antitumor …

[HTML][HTML] Targeting amino acid metabolism in cancer growth and anti-tumor immune response

E Ananieva - World journal of biological chemistry, 2015 - ncbi.nlm.nih.gov
Recent advances in amino acid metabolism have revealed that targeting amino acid
metabolic enzymes in cancer therapy is a promising strategy for the development of novel …

[HTML][HTML] Amino acid metabolism in tumor biology and therapy

J Chen, L Cui, S Lu, S Xu - Cell Death & Disease, 2024 - nature.com
Amino acid metabolism plays important roles in tumor biology and tumor therapy.
Accumulating evidence has shown that amino acids contribute to tumorigenesis and tumor …

[HTML][HTML] Amino acid transport and metabolism in myeloid function

MJ Halaby, TL McGaha - Frontiers in immunology, 2021 - frontiersin.org
Regulation of amino acid availability and metabolism in immune cells is essential for
immune system homeostasis and responses to exogenous and endogenous challenges …

[HTML][HTML] Amino acid metabolism in cancer drug resistance

HC Yoo, JM Han - Cells, 2022 - mdpi.com
Despite the numerous investigations on resistance mechanisms, drug resistance in cancer
therapies still limits favorable outcomes in cancer patients. The complexities of the inherent …

[HTML][HTML] Amino acid metabolism in health and disease

ZN Ling, YF Jiang, JN Ru, JH Lu, B Ding… - Signal Transduction and …, 2023 - nature.com
Amino acids are the building blocks of protein synthesis. They are structural elements and
energy sources of cells necessary for normal cell growth, differentiation and function. Amino …

[HTML][HTML] Amino acid transporters as targets for cancer therapy: why, where, when, and how

S Bröer - International journal of molecular sciences, 2020 - mdpi.com
Amino acids are indispensable for the growth of cancer cells. This includes essential amino
acids, the carbon skeleton of which cannot be synthesized, and conditionally essential …

[HTML][HTML] Amino acids in cancer

EL Lieu, T Nguyen, S Rhyne, J Kim - Experimental & molecular …, 2020 - nature.com
Abstract Over 90 years ago, Otto Warburg's seminal discovery of aerobic glycolysis
established metabolic reprogramming as one of the first distinguishing characteristics of …