[HTML][HTML] Amino acids and their transporters in T cell immunity and cancer therapy
W Wang, W Zou - Molecular cell, 2020 - cell.com
Metabolism reprogramming is critical for both cancer progression and effective immune
responses in the tumor microenvironment. Amino acid metabolism in different cells and their …
responses in the tumor microenvironment. Amino acid metabolism in different cells and their …
[HTML][HTML] Amino acid metabolism in immune cells: essential regulators of the effector functions, and promising opportunities to enhance cancer immunotherapy
L Yang, Z Chu, M Liu, Q Zou, J Li, Q Liu… - Journal of hematology & …, 2023 - Springer
Amino acids are basic nutrients for immune cells during organ development, tissue
homeostasis, and the immune response. Regarding metabolic reprogramming in the tumor …
homeostasis, and the immune response. Regarding metabolic reprogramming in the tumor …
Fueling T-cell antitumor immunity: amino acid metabolism revisited
C Han, M Ge, PC Ho, L Zhang - Cancer immunology research, 2021 - AACR
T cells are the key players in eliminating malignant tumors. Adoptive transfer of tumor
antigen-specific T cells and immune checkpoint blockade has yielded durable antitumor …
antigen-specific T cells and immune checkpoint blockade has yielded durable antitumor …
[HTML][HTML] Targeting amino acid metabolism in cancer growth and anti-tumor immune response
E Ananieva - World journal of biological chemistry, 2015 - ncbi.nlm.nih.gov
Recent advances in amino acid metabolism have revealed that targeting amino acid
metabolic enzymes in cancer therapy is a promising strategy for the development of novel …
metabolic enzymes in cancer therapy is a promising strategy for the development of novel …
[HTML][HTML] Amino acid metabolism in tumor biology and therapy
J Chen, L Cui, S Lu, S Xu - Cell Death & Disease, 2024 - nature.com
Amino acid metabolism plays important roles in tumor biology and tumor therapy.
Accumulating evidence has shown that amino acids contribute to tumorigenesis and tumor …
Accumulating evidence has shown that amino acids contribute to tumorigenesis and tumor …
[HTML][HTML] Amino acid transport and metabolism in myeloid function
MJ Halaby, TL McGaha - Frontiers in immunology, 2021 - frontiersin.org
Regulation of amino acid availability and metabolism in immune cells is essential for
immune system homeostasis and responses to exogenous and endogenous challenges …
immune system homeostasis and responses to exogenous and endogenous challenges …
[HTML][HTML] Amino acid metabolism in cancer drug resistance
Despite the numerous investigations on resistance mechanisms, drug resistance in cancer
therapies still limits favorable outcomes in cancer patients. The complexities of the inherent …
therapies still limits favorable outcomes in cancer patients. The complexities of the inherent …
[HTML][HTML] Amino acid metabolism in health and disease
ZN Ling, YF Jiang, JN Ru, JH Lu, B Ding… - Signal Transduction and …, 2023 - nature.com
Amino acids are the building blocks of protein synthesis. They are structural elements and
energy sources of cells necessary for normal cell growth, differentiation and function. Amino …
energy sources of cells necessary for normal cell growth, differentiation and function. Amino …
[HTML][HTML] Amino acid transporters as targets for cancer therapy: why, where, when, and how
S Bröer - International journal of molecular sciences, 2020 - mdpi.com
Amino acids are indispensable for the growth of cancer cells. This includes essential amino
acids, the carbon skeleton of which cannot be synthesized, and conditionally essential …
acids, the carbon skeleton of which cannot be synthesized, and conditionally essential …
[HTML][HTML] Amino acids in cancer
Abstract Over 90 years ago, Otto Warburg's seminal discovery of aerobic glycolysis
established metabolic reprogramming as one of the first distinguishing characteristics of …
established metabolic reprogramming as one of the first distinguishing characteristics of …