Myeloid-derived suppressor cells (MDSCs) contribute to tumor-mediated immune escape
and negatively correlate with overall survival of cancer patients. Nowadays, a variety of …

Myeloid-derived suppressor cells (MDSCs) are a heterogenic population of immature
myeloid cells with immunosuppressive effects, which undergo massive expansion during …

Suppression of antitumor immune responses is one of the main mechanisms by which tumor
cells escape from destruction by the immune system. Myeloid-derived suppressor cells …

The emergence of immunotherapy has been an astounding breakthrough in cancer
treatments. In particular, immune checkpoint inhibitors, targeting PD-1 and CTLA-4, have …

Simple Summary Myeloid-Derived Suppressor Cells (MDSCs) have been regarded as the
main promoters of cancer development in recent years. They can protect tumor cells from …

Among the various immunological and non-immunological tumor-promoting activities of
myeloid-derived suppressor cells (MDSCs), their immunosuppressive capacity remains a …

Under steady-state conditions, bone marrow-derived immature myeloid cells (IMC)
differentiate into granulocytes, macrophages and dendritic cells (DCs). This differentiation is …

Myeloid-derived suppressor cells (MDSCs) are a population of immature myeloid cells
defined by their immunosuppression. Elevated levels of certain soluble cytokines in tumor …

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature
myeloid cells that suppress innate and adaptive immunity. MDSCs are present in many …

Anticancer agents continue to dominate the list of newly approved drugs, approximately half
of which are immunotherapies. This trend illustrates the considerable promise of cancer …