Bilateral ovariectomy is the best characterized and the most reported animal model of
human menopause. Ovariectomized rodents develop insulin resistance (IR) and visceral …

Aims: Obesity is associated with insulin resistance, liver steatosis and low‐grade
inflammation. The role of oestrogen in sex differences in the above co‐morbidities is not fully …

Menopause, an age-related loss of ovarian hormone production, promotes increased
adiposity and insulin resistance. However, the diet-independent mechanism by which loss of …

Estrogen replacement therapy reduces the incidence of type 2 diabetes in postmenopausal
women; however, the mechanism is unknown. Therefore, the aim of this study was to …

Factors comprising the metabolic syndrome occur with increased incidence in
postmenopausal women. To investigate the effects of ovarian failure on the progression of …

AIMS: Long-term ovariectomy-induced metabolic changes such as insulin resistance and
glucose intolerance might be caused directly by estrogen deficiency and may occur partly as …

Objective The aim of this work was to evaluate the changes caused by estrogen deficiency
in lipid metabolism. Methods This study encompassed direct measurements of plasma …

The estrogen deficiency after menopause leads to overweight or obesity, and physical
exercise is one of the important modulators of this body weight gain. Female Wistar rats …

Postmenopausal women tend to have a higher risk in developing obesity and thus metabolic
syndrome. Recently we could demonstrate that physical activity and estrogen replacement …

Background: Although the prevalence of obesity is higher among women than men, they are
somewhat protected from the associated cardiometabolic consequences. The increase in …