Gentamicin is an aminoglycoside antibiotic with a small therapeutic window that is currently
used primarily as part of short-term empirical combination therapy. Gentamicin dosing …

Gentamicin is extensively used in the treatment of severe Gram-negative bacterial infections.
A loading dose of 7 mg/kg is recommended to achieve a maximum concentration (C max) …

Two doses of gentamicin (2 and 7 mg/kg of body weight) were administered to 11 healthy
volunteers in a randomized, crossover single-dose study to compare their pharmacokinetics …

The purpose of this study was to describe the population pharmacokinetics of gentamicin in
a group of 939 adult hospitalized patients receiving once-daily administration of gentamicin …

Background: Extended interval dosing (EID) of gentamicin most commonly involves dosing
every 24 hours, but patients with impaired renal function may require a longer dose interval …

Abstract Objectives The World Health Organization recommends that all children admitted
with severe malnutrition should routinely receive parenteral ampicillin and gentamicin; …

Population pharmacokinetic modelling, Monte Carlo simulation and semi-mechanistic
pharmacodynamic modelling are all tools that can be applied to personalize gentamicin …

What is known and objectives Gentamicin is often used for the treatment of Gram‐negative
infections. Due to pharmacokinetic variability in paediatric patients, appropriate dosing of …

When treating critically ill patients with gentamicin for severe infection, peak concentrations
(C max) determine clinical efficacy and trough concentrations (C min) determine toxicity …

Objectives Gentamicin is widely used in end-stage renal disease (ESRD) patients for the
treatment of infections. The goal of this study was to find the most reasonable dosing …