A novel erythroid-specific marker of transmissible spongiform encephalopathies
G Miele, J Manson, M Clinton - Nature Medicine, 2001 - nature.com
Transmissible spongiform encephalopathies (TSE) are a group of invariably fatal
neurodegenerative diseases and include scrapie in sheep, bovine spongiform …
neurodegenerative diseases and include scrapie in sheep, bovine spongiform …
Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie
NA Mabbott, ME Bruce, M Botto, MJ Walport… - Nature medicine, 2001 - nature.com
Following peripheral exposure to transmissible spongiform encephalopathies (TSEs),
infectivity usually accumulates in lymphoid tissues before neuroinvasion. The host prion …
infectivity usually accumulates in lymphoid tissues before neuroinvasion. The host prion …
Involvement of the immune system in TSE pathogenesis
NA Mabbott, CF Farquhar, KL Brown, ME Bruce - Immunology Today, 1998 - cell.com
Involvement of the immune system in TSE pathogenesis: Immunology Today Skip to Main
Content Advertisement Trends in Immunology This journal offers authors two options (open …
Content Advertisement Trends in Immunology This journal offers authors two options (open …
Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells
KL Brown, K Stewart, DL Ritchie, NA Mabbott… - Nature medicine, 1999 - nature.com
The immune system is central in the pathogenesis of scrapie and other transmissible
spongiform encephalopathies (TSEs) or'prion'diseases 1. After infecting by peripheral …
spongiform encephalopathies (TSEs) or'prion'diseases 1. After infecting by peripheral …
PrPSc in mammary glands of sheep affected by scrapie and mastitis
C Ligios, CJ Sigurdson, C Santucciu, G Carcassola… - Nature Medicine, 2005 - nature.com
Besides colonizing the central nervous system, the infectious agent of transmissible
spongiform encephalopathies, termed prion, is predominantly associated with follicular …
spongiform encephalopathies, termed prion, is predominantly associated with follicular …
Presymptomatic detection of prions in blood
Prions are thought to be the proteinaceous infectious agents responsible for transmissible
spongiform encephalopathies (TSEs). PrPSc, the main component of the infectious agent, is …
spongiform encephalopathies (TSEs). PrPSc, the main component of the infectious agent, is …
Homozygous prion protein genotype predisposes to sporadic Creutzfeldt–Jakob disease
MS Palmer, AJ Dryden, JT Hughes, J Collinge - Nature, 1991 - nature.com
THE human prion diseases, Creutzfeldt–Jakob disease (CJD) and Gerstmann–Sträussler
syndrome (GSS), are neurodegenerative diseases that are unique in being both infectious …
syndrome (GSS), are neurodegenerative diseases that are unique in being both infectious …
[HTML][HTML] Molecular assessment of the potential transmissibilities of BSE and scrapie to humans
GJ Raymond, J Hope, DA Kocisko, SA Priola… - Nature, 1997 - nature.com
More than a million cattle infected with bovine spongiform encephalopathy (BSE) may have
entered the human food chain. Fears that BSE might transmit to man were raised when …
entered the human food chain. Fears that BSE might transmit to man were raised when …
[引用][C] Human TSE disease—viral or protein only?
B Chesebro - Nature medicine, 1997 - nature.com
Untitled Page 1 Page 2 © 1997 Nature Publishing Group http://www.nature.com/naturemedicine
NEWS & VIEWS …
NEWS & VIEWS …
Unaltered susceptibility to BSE in transgenic mice expressing human prion protein
J Collinge, MS Palmer, KCL Sidle, AF Hill, I Gowland… - Nature, 1995 - nature.com
PRION diseases are transmissible neurodegenerative conditions of humans and animals.
Prions consist principally of a post-translationally modified form of prion protein (PrP), PrPSc …
Prions consist principally of a post-translationally modified form of prion protein (PrP), PrPSc …