Aphrodisiac Performance of Bioactive Compounds from Mimosa pudica Linn.: In Silico Molecular Docking and Dynamics Simulation Approach

C Palanichamy, P Pavadai, T Panneerselvam… - Molecules, 2022 - mdpi.com
Plants and their derived molecules have been traditionally used to manage numerous
pathological complications, including male erectile dysfunction (ED). Mimosa pudica Linn …

Mimosa pudica Linn. extract improves aphrodisiac performance in diabetes-induced male Wister rats

C Palanichamy, D Nayak Ammunje… - Journal of …, 2023 - Taylor & Francis
Male sexual dysfunction is considered one of the major consequences of diabetes mellitus.
The medicinal plant, Mimosa pudica Linn. is believed to have numerous therapeutic effects …

Computational screening and design of traditional Chinese medicine (TCM) to block phosphodiesterase-5

CYC Chen - Journal of Molecular Graphics and Modelling, 2009 - Elsevier
The traditional Chinese medicines (TCM), Epimedium sagittatum (ESs), Cnidium monnieri
(CMs), and Semen cuscutae (SCs), were used for treating erectile dysfunction since the …

Virtual screening and drug design for PDE-5 receptor from traditional Chinese medicine database

CYC Chen - Journal of Biomolecular Structure and Dynamics, 2010 - Taylor & Francis
Erectile dysfunction (ED) is a sexual disorder mainly caused by decrease in cellular
concentration of cyclic guanosine monophosphate (cGMP), which is degraded by …

In silico modeling revealed phytomolecules derived from Cymbopogon citratus (DC.) leaf extract as promising candidates for malaria therapy

IO Evbuomwan, OO Alejolowo, TC Elebiyo… - Journal of …, 2024 - Taylor & Francis
The emergence of varying levels of resistance to currently available antimalarial drugs
significantly threatens global health. This factor heightens the urgency to explore bioactive …

In silico analysis of Diosmetin as an effective chemopreventive agent against prostate cancer: molecular docking, validation, dynamic simulation and pharmacokinetic …

S Sheoran, S Arora, T Basu, S Negi… - Journal of …, 2023 - Taylor & Francis
Prostate cancer is the second most dangerous cancer type worldwide. While various
treatment options are present ie agonists and antagonists, their utilization leads to adverse …

Molecular modeling studies of natural inhibitors of androgen signaling in prostate cancer

SO Olubode, MO Bankole, PA Akinnusi… - Cancer …, 2022 - journals.sagepub.com
Prostate cancer is the second most common disease in men and the sixth leading cause of
death from cancer globally, with 20 million men expected to be affected by 2024 thus …

Exploring the potentials of some compounds from Garcinia kola seeds towards identification of novel PDE‐5 inhibitors in erectile dysfunction therapy

OA Ojo, AB Ojo, RF Maimako, D Rotimi… - Andrologia, 2021 - Wiley Online Library
Erectile dysfunction (ED) is one of the main challenges occurring among men worldwide,
and is characterised by trouble getting or keeping steady erection during sexual intercourse …

In silico identification of antidiabetic target for phytochemicals of A. marmelos and mechanistic insights by molecular dynamics simulations

P Sharma, T Joshi, S Mathpal, S Chandra… - Journal of …, 2022 - Taylor & Francis
The leaves and fruits of Aegle marmelos (L.) have antidiabetic activity. However, the mode of
action and molecules having antidiabetic activity are not known. Hence, we conducted …

[PDF][PDF] Assessment of anti-nociceptive and anthelmintic activities of Vitex Peduncularis Wall. leaves and in silico molecular docking, ADME/T, and PASS prediction …

RBJ Auniq, MNU Chy, M Adnan, A Roy… - J. Complement. Med …, 2019 - researchgate.net
ABSTRACT Background: Vitex peduncularis (Verbenaceae), popularly known as
“Boruna,”“Goda,”“Ashmul gaas”(Chakma),“Korobaong”(Marma), is frequently used in the …