Hydrogels are commonly used as artificial extracellular matrices for 3D cell culture and for
tissue engineering. Viscoelastic hydrogels with tunable stress relaxation have recently been …

Physical properties of the extracellular matrix (ECM) affect cell behaviors ranging from cell
adhesion and migration to differentiation and gene expression, a process known as …

The physical and architectural cues of the extracellular matrix (ECM) play a critical role in
regulating important cellular functions such as spreading, migration, proliferation, and …

Alginate-based hydrogels are extensively used matrices for cell encapsulation, but they
need to be modified to recapitulate chemical, microstructural, and mechanical properties of …

In tissues, many cells are surrounded by and interact with a three-dimensional soft
extracellular matrix (ECM). Both the physical and biochemical properties of the ECM play a …

Stress relaxation is an important design parameter of biomaterials that can provide an
artificial microenvironment mimicking natural extracellular matrix (ECM). Here, we report a …

Natural extracellular matrices (ECMs) are viscoelastic and exhibit stress relaxation.
However, hydrogels used as synthetic ECMs for three-dimensional (3D) culture are typically …

Hydrogels are increasingly used as a cell encapsulation and transplantation device. The
successful use of a hydrogel greatly relies on an ability to control hydrogel stiffness which …

Viscoelastic properties of hydrogels such as stress relaxation or plasticity have been
recognized as important mechanical cues that dictate the migration, proliferation, and …

There have been many demands for hydrogel systems in various biomedical applications. 1
Among them, hydrogels have been widely used for delivery systems of bioactive reagents …