Insomnia, sleep duration, and risk of anxiety: A two-sample Mendelian randomization study

F Zhou, S Li, H Xu - Journal of psychiatric research, 2022 - Elsevier
Background The effect of insomnia and sleep duration on risk of anxiety has been assessed
based on traditional epidemiological studies. However, the inconsistent conclusions do not …

[HTML][HTML] Exploring genetic association of insomnia with allergic disease and asthma: a bidirectional Mendelian randomization study

R Li, Y Chen, A Zhao, L Huang, Z Long, W Kang… - Respiratory …, 2022 - Springer
Background Insomnia is highly prevalent among patients with allergic disease and asthma;
however, few studies have investigated their causal relationship. We aim to explore the …

The bidirectional causal relationships of insomnia with five major psychiatric disorders: a Mendelian randomization study

X Gao, LX Meng, KL Ma, J Liang, H Wang… - European …, 2019 - cambridge.org
Background: Several observational studies have investigated the association of insomnia
with psychiatric disorders. Such studies yielded mixed results, and whether these …

Association between insomnia and migraine risk: a case–control and bidirectional mendelian randomization study

S Chu, Z Wu, Z Wu, J Wu, Y Qian - … and Personalized Medicine, 2021 - Taylor & Francis
Background The causal relationship between insomnia and migraine is contradictory and no
study has been carried out among the Chinese population to date. Methods In this case, we …

Mendelian randomization highlights insomnia as a risk factor for pain diagnoses

M Broberg, J Karjalainen, FinnGen, HM Ollila - Sleep, 2021 - academic.oup.com
Abstract Study Objective Insomnia has been linked to acute and chronic pain conditions;
however, it is unclear whether such relationships are causal. Recently, a large number of …

The heritability of insomnia: A meta‐analysis of twin studies

NL Barclay, D Kocevska, WM Bramer… - Genes, Brain and …, 2021 - Wiley Online Library
Twin studies of insomnia exhibit heterogeneity in estimates of heritability. This heterogeneity
is likely because of sex differences, age of the sample, the reporter and the definition of …

[HTML][HTML] Identifying the potential causal role of insomnia symptoms on 11,409 health-related outcomes: a phenome-wide Mendelian randomisation analysis in UK …

MJ Gibson, DA Lawlor, LAC Millard - BMC medicine, 2023 - Springer
Background Insomnia symptoms are widespread in the population and might have effects
on many chronic conditions and their risk factors but previous research has focused on …

Heritability of insomnia symptoms in youth and their relationship to depression and anxiety

PR Gehrman, LJ Meltzer, M Moore, AI Pack, ML Perlis… - Sleep, 2011 - academic.oup.com
Abstract Study Objectives: Insomnia is a highly prevalent sleep disorder yet little is known
about the role of genetic factors in its pathophysiology. The aim of this study was to examine …

Family history of insomnia in a population-based sample

S Beaulieu-Bonneau, M LeBlanc, C Mérette… - Sleep, 2007 - academic.oup.com
Abstract Study Objectives: To examine the rates of family history of insomnia in a population-
based sample composed of self-defined good sleepers and individuals with insomnia and …

Sleep disturbance and psychiatric disorders: a bidirectional Mendelian randomisation study

X Sun, B Liu, S Liu, DJH Wu, J Wang… - Epidemiology and …, 2022 - cambridge.org
Aims Sleep disturbance is an important factor in the pathophysiology and progression of
psychiatric disorders, but whether it is a cause, or a downstream effect is still not clear …