Many species of ganglioside GM1, differing for the sialic acid and ceramide content, have
been characterized and their physico-chemical properties have been studied in detail since …

Gangliosides (sialic acid-containing glycosphingolipids) are abundant in neurons of all
animal species and play important roles in many cell physiological processes, including …

Gangliosides are glycosphingolipids highly abundant in the nervous system, and carry most
of the sialic acid residues in the brain. Gangliosides are enriched in cell membrane …

GM1 ganglioside occurs widely in vertebrate tissues, where it exhibits many essential
functions, both in the plasma membrane and intracellular loci. Its essentiality is revealed in …

There is now substantial evidence that GM1 ganglioside is effective in partially correcting the
consequences of neuroinjury in a number of in vivo and in vitro model systems. Although the …

Gangliosides are glycosphingolipids localized to the outer leaflet of the plasma membrane
of vertebrate cells. The highest ganglioside concentration of any organ is found in the …

Gangliosides are cell membrane components, most abundantly in the central nervous
system (CNS) where they exert among others neuro-protective and-restorative functions …

Gangliosides, a heterogeneous family of glycosphingolipids abundant in the brain, have
been shown to affect neuronal plasticity during development, adulthood and aging. This …

Gangliosides, sialylated glycosphingolipids, found on all vertebrate cells and tissues, are
major molecular determinants on the surfaces of vertebrate nerve cells. Composed of a …

Lipid rafts, sites of signal transduction, are enriched in glycosphingolipids (GSLs).
Gangliosides, a class of GSLs found in greatest concentration in the grey matter of the brain …