Objective To investigate the impact of renin–angiotensin–aldosterone-system (RAAS)
inhibitors on complement component 4 (C4) serum levels in patients with immunoglobulin A …

Background An association between serum complement levels and poor renal prognosis in
patients with immunoglobulin A nephropathy (IgAN) remains controversial. Methods We …

Background The effects of low serum C3 levels and the activation of the complement system
on the development and the prognosis of IgAN are unclear. The present study aimed to …

Background: Aberrant activation of the complement system plays an important role in the
pathogenesis and development of immunoglobulin A nephropathy (IgAN). The relationship …

Aim The serum immunoglobulin A (IgA)/C3 ratio has been shown to be a good predictor of
histological lesions and prognosis for patients with IgA nephropathy (IgAN) in J apanese …

Background and aim Immunoglobulin A nephropathy (IgAN) is regarded as the most
common type of glomerulonephritis around the world and has the potential to result in renal …

Background Improvement of proteinuria as a marker for disease activity is associated with a
better renal outcome in immunoglobulin A nephropathy (IgAN). Complement is an effector …

Background After activation, the complement system is involved in the pathogenesis of
Immunoglobulin A nephropathy (IgAN). Complement factor H (CFH) is a crucial inhibitory …

Aim Complement activation is involved in the pathogenesis and progression of
immunoglobulin A nephropathy (IgAN); however, the clinical implication of abnormal …

Background There are few reports analyzing the effects of angiotensin-converting enzyme
inhibitors (ACEIs) and/or angiotensin receptor blockers (ARBs) on the long-term renal …