New insight into the mechanisms protecting bacteria during desiccation

E Laskowska, D Kuczyńska-Wiśnik - Current genetics, 2020 - Springer
Desiccation is a common stress that bacteria face in the natural environment, and thus, they
have developed a variety of protective mechanisms to mitigate the damage caused by water …

Trehalose protects Escherichia coli against carbon stress manifested by protein acetylation and aggregation

M Moruno Algara, D Kuczyńska‐Wiśnik… - Molecular …, 2019 - Wiley Online Library
The disaccharide trehalose is widely distributed in nature and can serve as a carbon
reservoir, a signaling molecule for controlling glucose metabolism and a stress protectant …

Trehalose is a versatile and long-lived chaperone for desiccation tolerance

H Tapia, DE Koshland - Current Biology, 2014 - cell.com
Background Diverse organisms across taxa are desiccation tolerant, capable of surviving
extreme water loss. Remarkably, desiccation tolerant organisms can survive years without …

Anhydrobiotic engineering of bacterial and mammalian cells: is intracellular trehalose sufficient?

A Tunnacliffe, AG de Castro, M Manzanera - Cryobiology, 2001 - Elsevier
Anhydrobiotic engineering aims to confer a high degree of desiccation tolerance on
otherwise sensitive living organisms and cells by adopting the strategies of anhydrobiosis …

Osmotically induced intracellular trehalose, but not glycine betaine accumulation promotes desiccation tolerance in Escherichia coli

DT Welsh, RA Herbert - FEMS Microbiology Letters, 1999 - academic.oup.com
Trehalose considerably increased the tolerance of Escherichia coli to air drying, whether
added as an excipient prior to drying or accumulated as a compatible solute in response to …

[HTML][HTML] Protein aggregation and glycation in Escherichia coli exposed to desiccation-rehydration stress

A Łupkowska, S Monem, J Dębski… - Microbiological …, 2023 - Elsevier
In natural environments, bacteria often enter a state of anhydrobiosis due to water loss.
Multiple studies have demonstrated that desiccation may lead to protein aggregation and …

Increasing intracellular trehalose is sufficient to confer desiccation tolerance to Saccharomyces cerevisiae

H Tapia, L Young, D Fox… - Proceedings of the …, 2015 - National Acad Sciences
Diverse organisms capable of surviving desiccation, termed anhydrobiotes, include species
from bacteria, yeast, plants, and invertebrates. However, most organisms are sensitive to …

Trehalose, reserve and/or stress metabolite?

A Van Laere - FEMS Microbiology Letters, 1989 - Elsevier
Trehalose is a ubiquitous disaccharide not only in fungi but also in different classes of
prokaryots, plants and animals [1]. This non-reducing disaccharide has, like its vegetal …

[HTML][HTML] Intracellular trehalose improves osmotolerance but not desiccation tolerance in mammalian cells

AG de Castro, A Tunnacliffe - FEBS letters, 2000 - Elsevier
Trehalose has been shown to play a role in osmotolerance or desiccation tolerance in some
microorganisms, anhydrobiotic invertebrates and resurrection plants. To test whether …

Trehalose synthesis is induced upon exposure of Escherichia coli to cold and is essential for viability at low temperatures

O Kandror, A DeLeon… - Proceedings of the …, 2002 - National Acad Sciences
Trehalose accumulates dramatically in microorganisms during heat shock and osmotic
stress and helps protect cells against thermal injury and oxygen radicals. Here we …