Background Functional cerebrovascular regulatory mechanisms are important for
maintaining constant cerebral blood flow and oxygen supply in heathy individuals and are …

Hypocapnia and endothelial dysfunction might impair microvascular cerebral blood flow
(CBF micr) and cerebrovascular reactivity to CO 2 (CVR CO2). Pulmonary arterial …

Background Arterial and thromboembolic pulmonary hypertension (PH) lead to arterial
hypoxaemia. Objective To investigate whether cerebral tissue oxygenation (CTO) in patients …

Exercise intolerance is a cardinal symptom of pulmonary arterial hypertension (PAH) and
strongly impacts patients9 quality of life (QoL). Although central cardiopulmonary …

This study examined cerebral blood flow (CBF) and its regulation before and after a short-
term periodized aerobic exercise training intervention in patients with chronic obstructive …

BACKGROUND: Pulmonary microcirculation abnormalities are the main determinants of
pulmonary arterial hypertension (PAH) pathophysiology. We hypothesized that PAH patients …

Patients with chronic obstructive pulmonary disease (COPD) may develop hypercapnia and
hypoxia, two main determinants of cerebral blood flow. The current authors tested whether …

Background Decline in oxygen uptake efficiency (OUE), especially during exercise, is found
in patients with chronic heart failure. In this study we aimed to test the validity and usefulness …

Background Pulmonary hypertension (PH) patients show, during exercise, an excessive
increase in ventilation (VE) compared to carbon dioxide output (VCO 2), determining a high …

Background: Patients with pulmonary hypertension (PH) may suffer from cognitive deficits
that potentially relate to reduced oxygen delivery and cerebral tissue oxygenation (CTO) …