Virtually all organisms on earth depend on transition metals for survival. Iron and copper are
particularly important because they participate in vital electron transfer reactions, and are …

Transition metal ions are essential nutrients to all forms of life. Iron, copper, zinc,
manganese, cobalt and nickel all have unique chemical and physical properties that make …

Exhaustive microarray time course analyses of Saccharomyces cerevisiae during copper
starvation and copper excess reveal new aspects of metal-induced gene regulation. Aside …

Eukaryotic cells contain dozens, perhaps hundreds, of iron-dependent proteins, which
perform critical functions in nearly every major cellular process. Nutritional iron is frequently …

Copper is an essential element in all forms of life. It acts as a cofactor of some enzymes and
is involved in forming proper protein conformations. However, excess copper ions in cells …

Iron and copper are cofactors for many enzymes and are stored, transported, and
sequestered by cells, but the complexities of their metabolism are not completely …

Fungi, like all free‐living organisms, are in competition for limiting nutrients. In accumulating
iron, fungi are faced also with a trace metal whose aqueous and redox chemistry make it …

Throughout evolution, all organisms have harnessed the redox properties of copper (Cu)
and iron (Fe) as a cofactor or structural determinant of proteins that perform critical functions …

Metal ions are vital to metabolism, as they can act as cofactors on enzymes and thus
modulate individual enzymatic reactions. Although many enzymes have been reported to …

This review addresses metal uptake specifically by yeast. Metal uptake may be passive,
active or both, depending on the viability of the biomass, and is influenced by a number of …