[HTML][HTML] Development of extra-fine particles containing nanosized meloxicam for deep pulmonary delivery: In vitro aerodynamic and cell line measurements

P Party, D Kókai, K Burián, A Nagy, B Hopp… - European Journal of …, 2022 - Elsevier
Pulmonary drug administration provides a platform for the effective local treatment of various
respiratory diseases. Application of nano-sized active ingredients results in higher …

Formulation and in vitro and in silico characterization of “nano-in-micro” dry powder inhalers containing meloxicam

P Party, C Bartos, Á Farkas, P Szabó-Révész… - Pharmaceutics, 2021 - mdpi.com
Pulmonary delivery has high bioavailability, a large surface area for absorption, and limited
drug degradation. Particle engineering is important to develop inhalable formulations to …

Formulation and comparison of spray dried non-porous and large porous particles containing meloxicam for pulmonary drug delivery

A Chvatal, R Ambrus, P Party, G Katona… - International journal of …, 2019 - Elsevier
Meloxicam is an anti-inflammatory drug that could be interesting to deliver locally to the
lungs to treat inflammation occurring in cystic fibrosis or chronic obstructive pulmonary …

Co-spray dried nafamostat mesylate with lecithin and mannitol as respirable microparticles for targeted pulmonary delivery: pharmacokinetics and lung distribution in …

JH Kang, YJ Kim, MS Yang, DH Shin, DW Kim, IY Park… - Pharmaceutics, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by a new strain of coronavirus called severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading rapidly worldwide …

Inhalation powder development without carrier: How to engineer ultra-flying microparticles?

A Lechanteur, E Gresse, L Orozco… - European Journal of …, 2023 - Elsevier
Particle engineering technologies have led to the commercialization of new inhaled
powders like PulmoSol TM or PulmoSphere TM. Such platforms are produced by spray …

A Novel Combined Dry Powder Inhaler Comprising Nanosized Ketoprofen-Embedded Mannitol-Coated Microparticles for Pulmonary Inflammations: Development, In …

H Banat, I Csóka, D Paróczai, K Burian, Á Farkas… - Pharmaceuticals, 2024 - mdpi.com
Pulmonary inflammations such as chronic obstructive pulmonary disease and cystic fibrosis
are widespread and can be fatal, especially when they are characterized by abnormal …

Preparation and Characterization of Ibuprofen Containing Nano-Embedded-Microparticles for Pulmonary Delivery

P Party, ML Klement, P Szabó-Révész, R Ambrus - Pharmaceutics, 2023 - mdpi.com
A fatal hereditary condition, cystic fibrosis (CF) causes severe lung problems. Ibuprofen
(IBU), a non-steroidal anti-inflammatory drug, slows the progression of disease without …

Sustainable strategies for nano-in-micro particle engineering for pulmonary delivery

AS Silva, MT Tavares, A Aguiar-Ricardo - Journal of nanoparticle research, 2014 - Springer
With the increasing popularity and refinement of inhalation therapy, there has been a huge
demand for the design and development of fine-tuned inhalable drug particles capable of …

Optimization of spray drying process parameters for the preparation of inhalable mannitol-based microparticles using a Box-Behnken experimental design

J Karas, S Pavloková, H Hořavová, J Gajdziok - Pharmaceutics, 2023 - mdpi.com
Inhalation is used for local therapy of the lungs and as an alternative route for systemic drug
delivery. Modern powder inhalation systems try to target the required site of …

Aerodynamic properties and in silico deposition of meloxicam potassium incorporated in a carrier-free DPI pulmonary system

A Chvatal, Á Farkas, I Balásházy… - International Journal of …, 2017 - Elsevier
Dry powder inhalers (DPIs) have been among the fastest developing inhaler forms in the
past decades. Researches are focusing on the formulation of carrier-free powders to obtain …