Long-circulating and target-specific nanoparticles: theory to practice

SM Moghimi, AC Hunter, JC Murray - Pharmacological reviews, 2001 - ASPET
The rapid recognition of intravenously injected colloidal carriers, such as liposomes and
polymeric nanospheres from the blood by Kupffer cells, has initiated a surge of development …

[HTML][HTML] Active cellular and subcellular targeting of nanoparticles for drug delivery

OK Nag, JB Delehanty - Pharmaceutics, 2019 - mdpi.com
Nanoparticle (NP)-mediated drug delivery (NMDD) for active targeting of diseases is a
primary goal of nanomedicine. NPs have much to offer in overcoming the limitations of …

[HTML][HTML] Therapeutic nanoparticles and their targeted delivery applications

AA Yetisgin, S Cetinel, M Zuvin, A Kosar, O Kutlu - Molecules, 2020 - mdpi.com
Nanotechnology offers many advantages in various fields of science. In this regard,
nanoparticles are the essential building blocks of nanotechnology. Recent advances in …

Targeted drugs and nanomedicine: present and future

P Debbage - Current pharmaceutical design, 2009 - ingentaconnect.com
Packaging small-molecule drugs into nanoparticles improves their bio-availability, bio-
compatibility and safety profiles. Multifunctional particles carrying large drug payloads for …

[HTML][HTML] A brief history of long circulating nanoparticles

HB Haroon, AC Hunter, ZS Farhangrazi… - Advanced Drug Delivery …, 2022 - Elsevier
The propensity of the hepatic macrophages (Kupffer cells) to rapidly intercept particulate
materials from the blood has been frustrating in redirecting intravenously injected …

The Effect of Nanoparticle Size on In Vivo Pharmacokinetics and Cellular Interaction

N Hoshyar, S Gray, H Han, G Bao - Nanomedicine, 2016 - Taylor & Francis
Nanoparticle-based technologies offer exciting new approaches to disease diagnostics and
therapeutics. To take advantage of unique properties of nanoscale materials and structures …

[图书][B] Multifunctional nanoparticles for drug delivery applications: imaging, targeting, and delivery

S Svenson, RK Prud'homme - 2012 - books.google.com
This book clearly demonstrates the progression of nanoparticle therapeutics from basic
research to applications. This book, unlike others covering nanoparticles used in medical …

Challenges in realizing selectivity for nanoparticle biodistribution and clearance: lessons from gold nanoparticles

DV Haute, JM Berlin - Therapeutic delivery, 2017 - Taylor & Francis
The field of nanomedicine has received much attention for its potential to allow for targeted
identification and treatment of tumors, while sparing healthy tissue. This promise has yet to …

Nanoparticles in cellular drug delivery

AH Faraji, P Wipf - Bioorganic & medicinal chemistry, 2009 - Elsevier
This review highlights the properties of nanoparticles used in targeted drug delivery,
including delivery to cells as well as organelle targets, some of the known pharmacokinetic …

Nanoparticles in the clinic

AC Anselmo, S Mitragotri - Bioengineering & translational …, 2016 - Wiley Online Library
Nanoparticle/microparticle‐based drug delivery systems for systemic (ie, intravenous)
applications have significant advantages over their nonformulated and free drug …