[HTML][HTML] Co-Treatment of Caco-2 Cells with Doxorubicin and Gold Nanoparticles Produced from Cyclopia intermedia Extracts or Mangiferin Enhances Drug Effects

JA Aboyewa, NRS Sibuyi, M Goboza, LA Murtz… - Nanomaterials, 2022 - mdpi.com
Mangiferin (MGF) is a natural and valuable polyphenol found in significant levels in many
plant species, including Cyclopia intermedia (C. intermedia). In a previous study, we …

[HTML][HTML] Gold Nanoparticles Synthesized Using Extracts of Cyclopia intermedia, Commonly Known as Honeybush, Amplify the Cytotoxic Effects of Doxorubicin

JA Aboyewa, NRS Sibuyi, M Meyer, OO Oguntibeju - Nanomaterials, 2021 - mdpi.com
Cyclopia intermedia (C. intermedia) is an indigenous South African shrub used to prepare
the popular medicinal honeybush (HB) tea. This plant contains high levels of mangiferin …

[PDF][PDF] In-vitro antioxidant and cytotoxic activities of silver nanoparticles of mangiferin isolated from Mangifera indica

SNN Othman, M Seka - Journal of Global Pharma Technology, 2019 - researchgate.net
The present study aimed to synthesize mangiferin AgNPs and evaluate its in vitro
antioxidant and cytotoxic properties. Mangiferin AgNPs was prepared using silver nitrate …

In Vitro Study of the Cytoprotective and Antimutagenic Potential of Mangiferin Encapsulated Nanoparticles

R Samadarsi, A Nayak, D Dutta - BioNanoScience, 2024 - Springer
Free radicals generated during the metabolic process are elevated in tumor cells. Natural
antioxidants like polyphenols are considered a promising chemotherapeutic to alleviate …

Effect of curcumin-loaded nanoparticles on mitochondrial dysfunctions of breast cancer cells

Y Wang, Z Luo, Z Wang, M You, S Xie, Y Peng… - Journal of Nanoparticle …, 2018 - Springer
Curcumin exhibits excellent anticancer and antibacterial activities. However, this compound
has poor solubility and lower bioavailability, which limits its therapeutic efficacy. To improve …

Synthesis and characterization of mangiferin loaded n, o-cmc nanoparticles and its cytotoxic effect on osteosarcoma mg-63 cells

PZS Yusri, NF Ghazali, NA Mazlan… - … Journal of Research …, 2020 - research.monash.edu
Mangiferin is a xanthone glycoside, naturally isolated from Mangifera indica. Mangiferin has
been reported for a wide range of pharmacological activities and its anticancer potential is …

[HTML][HTML] Folate-mediated mitochondrial targeting with doxorubicin-polyrotaxane nanoparticles overcomes multidrug resistance

H Wang, H Yin, F Yan, M Sun, L Du, W Peng, Q Li… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Resistance to treatment with anticancer drugs is a significant obstacle and a fundamental
cause of therapeutic failure in cancer therapy. Functional doxorubicin (DOX) nanoparticles …

[HTML][HTML] Anticancer and Drug-Sensitizing Activities of Gold Nanoparticles Synthesized from Cyclopia genistoides (Honeybush) Extracts

JR Sharma, NRS Sibuyi, AO Fadaka, S Meyer… - Applied Sciences, 2023 - mdpi.com
Synthesis of gold nanoparticles (AuNPs) using phytochemicals has become tremendously
prominent in biomedical applications because of its enhanced bioactivity and …

[HTML][HTML] Suppressive activities of mangiferin on human epithelial ovarian cancer

Z Zeng, C Lin, S Wang, P Wang, W Xu, W Ma, J Wang… - Phytomedicine, 2020 - Elsevier
Background Epithelial carcinoma is a subtype of ovarian cancers, with the highest lethality
among all ovarian cancer subtypes. Hitherto surgical excision combined with chemotherapy …

[HTML][HTML] Nanoparticle delivery of artesunate enhances the anti-tumor efficiency by activating mitochondria-mediated cell apoptosis

R Liu, X Yu, C Su, Y Shi, L Zhao - Nanoscale Research Letters, 2017 - Springer
Artemisinin and its derivatives were considered to exert a broad spectrum of anti-cancer
activities, and they induced significant anti-cancer effects in tumor cells. Artemisinin and its …