This thesis describes investigations performed using a time-resolved optical tomographic
medical imaging system. Optical tomography involves transilluminating a volume of tissue …

Diffuse optical tomography, also known as near infrared tomography, has been under
investigation, for non‐invasive functional imaging of tissue, specifically for the detection and …

Near-infrared (NIR) tomography is a technique used to measure light propagation through
tissue and generate images of internal optical property distributions from boundary …

A multispectral direct chromophore and scattering reconstruction technique has been
implemented for near-infrared frequency-domain tomography in recovering images of total …

A near-infrared (NIR) imaging system is evaluated as a diagnostic clinical tool to image total
hemoglobin concentration and oxygen saturation within tissue. Calibration of this type of …

In vivo tissue imaging using near-infrared light suffers from low spatial resolution and poor
contrast recovery because of highly scattered photon transport. For diffuse optical …

Near-infrared (NIR) light has the potential to be used as a non-invasive means of diagnostic
imaging within the human breast. Due to the diffusive nature of light in tissue, computational …

Quantitative near infrared (NIR) imaging of tissue requires the use of a diffusion model-
based reconstruction algorithm, which solves for the absorption and scattering coefficients of …

We present the Toast++ open-source software environment for solving the forward and
inverse problems in diffuse optical tomography (DOT). The software suite consists of a set of …

A novel parallel source implementation approach to near-infrared tomography is
demonstrated through spectral encoding of the light delivery. This new technique allows …