Background Diclofenac (DF) is a non-steroidal anti-inflammatory drug (NSAID) generally
prescribed for the treatment of pain. In spite of the widespread use of DF, hepatotoxicity has …

Cyclophosphamide (CYP) is a chemotherapeutic agent used in the treatment of autoimmune
disorders and malignant diseases. However, its usage is restricted due to its severe side …

Abstract Aims Paclitaxel (Pax) is a chemotherapeutic drug from the taxane family that is used
in the treatment of human cancer, including ovarian, breast, and non-small cell lung …

Paracetamol (PC) is a widely used analgesic and antipyretic drug, but it leads to acute
hepatotoxicity at high doses intakes. This study was aimed to investigate the effects of …

Abstract Resumen Context: Diclofenac (DIC) is known for its anti-inflammatory and
analgesic properties but liver toxicity is one of the main targets to use this drug. Previous …

The presented study was performed to verify whether rutin and/or quercetin can inhibit liver
injury induced by doxorubicin (DXR) in male Wistar rats. In this study, male Wistar rats were …

This study is aimed at evaluating the preventive effect and at suggesting the mode of actions
of naringin and hesperidin and their combination in diclofenac‐induced hepatotoxicity. Male …

Paracetamol (PC) is a safe analgesic and antipyretic drug at therapeutic doses, and it is
widely used in clinics. However, at high doses, it can induce hepatotoxicity and …

Background Cisplatin is an effective and extensively used chemotherapeutic agent to treat
range of malignancies, but its therapeutic use is limited because of dose-dependent …

Chrysophanol (Chr), one of the major anthraquinones extracted from rhubarb, has been
reported to possess various pharmacological properties including anti-cancer, antimicrobial …