Osteosarcoma (OS) is one of the most common bone cancers that constantly affects
children, teenagers, and young adults. Numerous epigenetic elements, such as miRNAs …

Osteosarcoma is the most common bone cancer in children and young adults. Surgery and
multi-agent chemotherapy are the standard treatment regimens for this disease. New …

Osteosarcoma (OS) is the most common primary malignant bone tumor, usually arising in
the long bones of adolescents and young adults. While our knowledge of the molecular …

MicroRNAs (miRNAs) involved in key signaling pathways and aggressive phenotypes of
osteosarcoma (OS) was discussed, including PI3K/AKT/MTOR, MTOR AND RAF-1 …

MicroRNAs (miRNAs) are small RNA molecules, which can interfere with the expression of
several genes and act as gene regulator. miRNAs have been proved as a successful …

Osteosarcoma (OS) is one of the most common malignant tumors derived from
mesenchymal tissue and is highly invasive, mainly in children and adolescents. Treatment of …

Osteosarcoma (OS) is the most common primary bone cancer in children and adolescents,
but its pathogenesis has been difficult to establish because of its well-known heterogeneous …

Osteosarcoma is one of the most prevalent primary bone tumors with a high metastatic and
recurrence rate with poor prognosis. MiRNAs are short and non-coding RNAs that could …

Background Osteosarcomas are the most common primary malignant tumors of bone and
show multiple and complex genomic aberrations. miRNAs are non-coding RNAs capable of …

Osteosarcoma is an aggressive sarcoma of the bone characterized by a high level of genetic
instability and recurrent DNA deletions and amplifications. This study assesses whether …