Identification of a highly specific hydroxyapatite‐binding peptide using phage display

MD Roy, SK Stanley, EJ Amis, ML Becker - Advanced Materials, 2008 - Wiley Online Library
A peptide sequence SVSVGMKPSPRP that selectively recognizes hydroxyapatite (HA) is
identified by using a phage display approach. The engineered sequence exhibits chemical …

Phosphorylation-dependent mineral-type specificity for apatite-binding peptide sequences

WN Addison, SJ Miller, J Ramaswamy, A Mansouri… - Biomaterials, 2010 - Elsevier
Apatite-binding peptides discovered by phage display provide an alternative design method
for creating functional biomaterials for bone and tooth tissue repair. A limitation of this …

Quantification of the binding affinity of a specific hydroxyapatite binding peptide

MC Weiger, JJ Park, MD Roy, CM Stafford, A Karim… - Biomaterials, 2010 - Elsevier
The genesis of bone and teeth involves highly coordinated processes, which involve
multiple cell types and proteins that direct the nucleation and crystallization of inorganic …

In vitro labeling of hydroxyapatite minerals by an engineered protein

E Yuca, AY Karatas, UOS Seker… - Biotechnology and …, 2011 - Wiley Online Library
Biological and biomimetic synthesis of inorganics have been a major focus in hard tissue
engineering as well as in green processing of advanced materials. Among the minerals …

Evolutionary screening of collagen-like peptides that nucleate hydroxyapatite crystals

WJ Chung, KY Kwon, J Song, SW Lee - Langmuir, 2011 - ACS Publications
The biogenesis of inorganic/organic composite materials such as bone typically involves the
process of templated mineralization. Biomimetic synthesis of bone-like materials therefore …

Regulation of in vitro calcium phosphate mineralization by combinatorially selected hydroxyapatite-binding peptides

M Gungormus, H Fong, IW Kim, JS Evans… - …, 2008 - ACS Publications
We report selection and characterization of hydroxyapatite-binding heptapeptides from a
peptide− phage library and demonstrate the effects of two peptides, with different binding …

[HTML][HTML] Identification of specific hydroxyapatite {001} binding heptapeptide by phage display and its nucleation effect

J Mao, X Shi, YB Wu, SQ Gong - Materials, 2016 - mdpi.com
With recent developments of molecular biomimetics that combine genetic engineering and
nanotechnology, peptides can be genetically engineered to bind specifically to inorganic …

Biomimetic synthesis of calcium-deficient hydroxyapatite in a natural hydrogel

SA Hutchens, RS Benson, BR Evans, HM O'Neill… - Biomaterials, 2006 - Elsevier
A novel composite material consisting of calcium-deficient hydroxyapatite (CdHAP)
biomimetically deposited in a bacterial cellulose hydrogel was synthesized and …

Self assembled bi-functional peptide hydrogels with biomineralization-directing peptides

M Gungormus, M Branco, H Fong, JP Schneider… - Biomaterials, 2010 - Elsevier
A peptide-based hydrogel has been designed that directs the formation of hydroxyapatite.
MDG1, a twenty-seven residue peptide, undergoes triggered folding to form an …

Dual-functioning peptides discovered by phage display increase the magnitude and specificity of BMSC attachment to mineralized biomaterials

H Ramaraju, SJ Miller, DH Kohn - Biomaterials, 2017 - Elsevier
Abstract Design of biomaterials for cell-based therapies requires presentation of specific
physical and chemical cues to cells, analogous to cues provided by native extracellular …