The neurovascular unit, which protects neuronal cells and supplies them with essential
molecules, plays an important role in the pathophysiology of Alzheimer's Disease (AD). The …

Neurovascular dysfunction, including blood–brain barrier (BBB) breakdown and cerebral
blood flow (CBF) dysregulation and reduction, are increasingly recognized to contribute to …

Purpose To investigate whether the blood-brain barrier (BBB) leaks blood-circulating
substances in patients with early forms of Alzheimer disease (AD), and if so, to examine the …

BACKGROUND: Our objectives were to compare the effects of subcortical ischemic vascular
dementia (SIVD) and Alzheimer's disease (AD) on cerebral blood flow (CBF), and then to …

Blood-brain barrier (BBB) dysfunction may contribute to the risk of Alzheimer's disease (AD).
Dynamic contrast-enhanced magnetic resonance imaging (MRI) was performed repeatedly …

Blood-brain barrier (BBB) separates the systemic circulation and the brain, regulating
transport of most molecules to protect the brain microenvironment. Multiple structural and …

In vascular dementia (VaD) and Alzheimer's disease (AD), cerebral hypoperfusion and
blood‐brain barrier (BBB) leakiness contribute to brain damage. In this study, we have …

Purpose To measure the cerebrovascular volume and blood‐brain barrier (BBB)
permeability indices in hippocampus and cerebellum of patients with mild cognitive …

Increasing evidence indicates that blood–brain barrier (BBB) impairment may play a role in
the pathophysiology of cognitive decline and dementia. In vivo imaging studies are needed …

Background Alzheimer's disease (AD) dementia is a consequence of heterogeneous and
complex interactions of age-related neurodegeneration and vascular-associated …