Conventional chemotherapy lacking target selectivity often leads to severe side effects,
limiting the effectiveness of chemotherapy. Therefore, drug delivery systems ensuring both …

Receptor‐mediated drug delivery presents an opportunity to enhance therapeutic efficiency
by accumulating drug within the tissue of interest and reducing undesired, off‐target effects …

For the purpose of this review, active targeting in cancer research encompasses strategies
wherein a ligand for a cell surface receptor expressed on tumor cells is used to deliver a …

Targeted delivery combined with controlled release of drugs has a crucial role in future of
personalized medicine. The majority of cancer drugs are intended to interfere with one or …

Safety and efficacy constitute the major criteria governing regulatory approval of any new
drug. The best method to maximize safety and efficacy is to deliver a proven therapeutic …

Targeted delivery of anticancer drugs to cancer cells and tissues is a promising field due to
its potential to spare unaffected cells and tissues, but it has been a major challenge to …

Traditional cancer chemotherapy easily produces serious toxic and side effects due to the
lack of specific selection of tumor cells, which restricts its curative effect. Targeted delivery …

Chemotherapy has been the main modality of treatment for cancer patients; however, its
success rate remains low, primarily due to limited accessibility of drugs to the tumor tissue …

Background: Limited accessibility of drugs to the tumor tissues, the requirement of high
doses, intolerable cytotoxicity, the development of multiple drug resistance and non-specific …

Conventional chemotherapeutics exploration is hampered due to their nonspecific
distribution leading to unintended serious toxicity. Toxicity is so severe that deciding to go for …