In situ glomerular expression of activated NF-κB in human lupus nephritis and other non-proliferative proteinuric glomerulopathy

L Zheng, R Sinniah, S I-Hong Hsu - Virchows Archiv, 2006 - Springer
Abstract Nuclear Factor-κB (NF-κB) has been suggested to play a role in the cellular and
molecular mechanisms underlying glomerular injury. We investigated the potential role of …

Pathogenic role of NF-κB activation in tubulointerstitial inflammatory lesions in human lupus nephritis

L Zheng, R Sinniah, SIH Hsu - Journal of Histochemistry & …, 2008 - journals.sagepub.com
In vitro and in vivo experimental studies suggest that the transcription factor NF-κB plays a
role in tubulointerstitial injury. We investigated possible cellular and molecular mechanisms …

[HTML][HTML] Tubular NF-κB and AP-1 activation in human proteinuric renal disease

SA Mezzano, M Barría, MA Droguett, ME Burgos… - Kidney international, 2001 - Elsevier
Tubular NF-κB and AP-1 activation in human proteinuric renal disease. Background Nuclear
factor-κB (NF-κB) and activated protein-1 (AP-1) are transcription factors that regulate many …

Activation of transcription factor NF-κB in experimental glomerulonephritis in rats

H Sakurai, Y Hisada, M Ueno, M Sugiura… - … et Biophysica Acta (BBA …, 1996 - Elsevier
NF-κB plays a pivotal role in cells of the immune system as an inducible transcriptional
activator. NF-κB regulates the transcription of many genes of pro-inflammatory cytokines and …

NF-κB in renal inflammation

AB Sanz, MD Sanchez-Niño, AM Ramos… - Journal of the …, 2010 - journals.lww.com
The NF-κB family of transcription factors regulates the induction and resolution of
inflammation. Two main pathways, classical and alternative, control the nuclear …

Renal cell apoptosis and proliferation may be linked to nuclear factor–κB activation and expression of inducible nitric oxide synthase in patients with lupus nephritis

L Zheng, R Sinniah, I Stephen, H Hsu - Human pathology, 2006 - Elsevier
The mechanism of renal cell apoptosis involves transcriptional activation of the inducible
nitric oxide synthase (iNOS) gene by nuclear factor (NF)-κB. The role of apoptosis in …

[HTML][HTML] Activation of nuclear factor-κB by podocytes in the autologous phase of passive Heymann nephritis

SJ Mudge, K Paizis, RB Auwardt, RJ Thomas… - Kidney international, 2001 - Elsevier
Activation of nuclear factor-κB by podocytes in the autologous phase of passive Heymann
nephritis. Background The present study examined whether activation of nuclear factor-κB …

Detection of nuclear factor-κB in IgA nephropathy using Southwestern histochemistry

M Ashizawa, M Miyazaki, K Abe, A Furusu… - American journal of …, 2003 - Elsevier
BACKGROUND:: The transcription factor nuclear factor-κB (NF-κB) is involved in
inflammatory and immune responses through induction of various cytokines and growth …

[HTML][HTML] Suppression of NF-κB and AP-1 activation by glucocorticoids in experimental glomerulonephritis in rats: Molecular mechanisms of anti-nephritic action

H Sakurai, N Shigemori, Y Hisada, T Ishizuka… - … et Biophysica Acta (BBA …, 1997 - Elsevier
Transcription factors nuclear factor-κB (NF-κB) and activator protein-1 (AP-1) play an
important role in the induction of pro-inflammatory factors such as cytokines and cell …

The NF-κB1 is a key regulator of acute but not chronic renal injury

A Fearn, GR Situmorang, C Fox, F Oakley… - Cell death & …, 2017 - nature.com
The NF-κB family of transcription factors is important for many cellular functions, in particular
initiation and propagation of inflammatory and immune responses. However, recent data …